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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EIF6 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3692 Official gene symbol EIF6 Full name eukaryotic translation initiation factor 6 Aliases ,2,CAB,EIF3A,ITGB4BP,b,b(2)gcn,gcn,p27BBP, Gene summary Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 20   Locus: 20q12 Gene position 33872594 - 33866725  Map Viewer Gene orientation minus Gene size 5870 bp Gene sequence >EIF6:complement(4062817..4068686):Length=5870 AACGGAAACCTTTTTAGGGAGTCCAAGGTACAGTCGCCGCGTGCGGAGCTTGTTACTGGT TACTTGGTAAGCTGGTGTGAGGGGAACCTGGGAGGGTCAGCTCCGGTCCTGGGTCGGGAG GGGTGGGGGCCAGAGGATTCAGGGCCGGAGGTTCTGGTGGGGGCCCAGTGGGCGGGACCC GAGGACGGAGGGGCCGGGAGGCCGAGAGGGGCGGGGTCGCGGCGGGGCCTGAGGGACGGA GGCCGGGATACTTGGGAAAGGATCCGCCGGCCTTGAACTCCCGCCTCCGCCGCCCCTAGG CCTCATGGCGGTCCGAGCTTCGTTCGAGAACAACTGTGAGATCGGCTGCTTTGCCAAGCT CACCAACACCTACTGTCTGGTAGCGATCGGAGGCTCAGAGAACTTCTACAGGTGCGGCGG GAGCCCCGGGGCTTACGGTGGCGGGGAGGCGTGCGCAGGAGTCAAGAGCTCCGGCAGTGG GAGGGTGCCGGCCCCTCTGCCCCGCCACCACCGAGTCCATGTCCCTACAGTGTGTTCGAG GGCGAGCTCTCCGATACCATCCCCGTGGTGCACGCGTCTATCGCCGGCTGCCGCATCATC GGGCGCATGTGTGTGGGTAAGGCAGGTGGAGGACGCCGAGGGAGGGAGTGGTCTCCAAGC ACCATTAATTACACCCCCGGAGGGAACCCGGAGTGACCTAGGGATTCCCAGGGTATCATC TGTTATCTCTGGGCACTATAGAATCTCTCAGGCCAAGCGTCAGGAGATCGGGGCAACCCT CTAGCAAAGGCTGCTGGATAATAGTAATAACAAATAATGTAAAGTGCTTTCACTCCTGTT CTCATTCCTTCGTCACAAAGACACTAGAAGGTAGGAGTTACTGGCCTAACTTGACTGATG AGGAAGTTGAGACTTGACCTAAGTGACTCAGTAAGTTCCACACCTAGTTCCTAGTGTTGG AGAAGGATTTTTCTCTTTTTTTTTTTTTTTTGAGGCCAGATTTTTGCTCTTTCGCCCAGG CTGGAGTGCAGTGGCAAGATCACAGCTGTCTGCATCCTCAACTTCTTAGGCTCAAGTGAT CCTCCCACCTCAGCCTACCAGGTAGCTAGGGCCACAGGCACGTGCCACCACACCTGGCTA ATTTTTACATTTTTGGTAGAGACGCGGCCTCCCTGTGTTGCCCAGCCTGGCCTTGATCTC CTGGGCTCAAGTGATCTTCTTACCTTGGTCTCTTAAAGTGTTGGGATTATAGGCGAGAGC CACTATACCCAGCCGAGGATTTGTATCTCATCTCTCCCTGCCACTGACTGGGCAAGGTGC TTTCTCTTTCTAAGCATCCATTTCTGTCTCTGTAAAGATTAGCTAAGATATGCGGTCTTC CTGCTCAGTTACGTTGGAATCTTAAATTCCCTTTACCACATCTCTACCCTACCTTCCTAC CTGTCAGCACTGTTAATTCTGGTCGTTGGTCCTTTCCTTTTTATTATTATTATTATTTTT TTTTGAGATGGAGTTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTTGGC TCACTGCAACACTCTCTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTA CAGGCGCATCCCGCCACACCCGGCTAATTTTTTTGTATTTTTAGTAGAGATGGAGTTTCA CCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCTCCCACCTCGGCCTC CCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCGGTCCTTTCATTAAGCTG GATCTGTCTTCCATTACTGCTGCCCATTGTTTCTTAGTTCTGCTCATTGAGGTCACTTTT AGAAGTCTGTTTATTTTATTTTTTTACTTTTACTTTAATTTTTAAAAATCTTAAGCCTGC TTGGGAGGTCGAGGCAGGTGGATCACCTGAGGTCAGCAGTTCGAGACTAACCTGACCAAC ATGGAGAAACCCCGTCTCTACTAAAAATACAGAAATTAGCCGGGTGTGGTGGCGCATACC TATAATCCCAGCTACTTGGGAGGCTGAGGCGGGAGAATTGCTTGAACCCTGGAGGTGGAG CTCACCCTGCGGTGAGCTGAGATTGTGCCATTGCATTTCAGCCTGGGCAATAAGAGTGAA ACTGTGTCTCAAAAAAAAACAAAAAACAAAAAACAACAACAACAAAAACTTAAGCCTAGT GACCTCAAAGTATTTTCCTATTCAGTTAAAATACTCTGATCTCTAACCATGCCCTTAGGA CTTGAAGCAAGTTCTGACAACAAGGGAGATTTTAGCTTAGTCCTTGTGTATTTTATGATG GGAGTGACCTGGAATTCAGAAATTGATTGGCGTGTATTTGTAGATTGTTCATTCTTGTTG CTGTATGGTGTGTTTTGTGTAAGTATATCACAACGTATTCATCCATTCCATCGACAGTGC ATTTGGGCAGTTTTCACTTTGGTCTGTTAGGAATAGTGCTGCTGGCCGGGCATGGTGGCT CACGCCTGTAATCCCAGCACTCTGGGAGGCCGAGGCGGGCGGATCACGAGGTCGGGAGAT CGAGACCATCCTGGTTAACACGGTGAAACCCCGTGTCTACTAAAAATACAAAAAAATTAG CCAGGTGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTTGGGAGGTTGAGGCAGGAGAATG GTGTGAACCGGGGAGGTAGAACTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCT GGGCAACAGAACAAGACTCCGTCTCAAAAAAAAAAAAAAAAGTAATAGTGCTGCTATGTT TTTTTAGTGAACACATGTACATATTTCTACTGGGTATATGATACCTAAGAGTGGCATGGC AGAGTCACAGGTTATGTGACTATTTAGTAGTAGTTGCAGATGATGCCAGATAATTATCTA AAGTGATTGACCAACTTACACTCCTGTCTCAGTATGAGAGTTCAGTTGCTCCATATATCT TTGCCAACACTTGGAATTGATGACTTGTAAAAATTTTAGTCATTCTGGCTGGGGGCAGTG GCTCACACCTGTAATCGTAGCACTTTGGGAGGTCGAGGTGGGCGGATCACCTGAGGTTAG GAGTTCGAGACCAGCCTGGCCAACATAGTGAGACCCCATCTCTACAAAATCACAAAAAGT TAGCCAGGTGTGGTGGCACGCACTTGTAATTCCAGCTACTCAGGAGGCCGAAGCAGGAGA ATCACCTGAACCCAGGATGCAGAAGTTGCAGTGAGCTGAGATCGCACCACTGCGCTCCAG CCTGGGTGACAGAGTGAGACTCTGCCTTAAAAAATAATAATCTAGCCATTCTGCTATGTG TGTAGTGTTAGCTCAGTTTTTTTTGTTTTTTTGTTTTTTTTTTTTGGAGACGGAGTTTCG CTCTGTCACCCAGGTTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCC CGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCC ACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAG GATGATCTCGATCTCGATCTCCTGACCTTGTGATCTGCCCACCTCAGCCTCCCAAAGTGC TGGGATTACAGGCGTGAGCCAACACGCCCGGCAGCTCAGTTTTTAAGTAGCAAAATATAC AGCTAATGCCAAGAGCTCAGCTTCCCTCCCAGTTGGTGATGGTGAAGTAGGCAGGATTTA TTGGGATTCCTGGGTGGTCTCTGGCCTGCCCTGGGTGTTTTCCAGATCAGTGGGTTGGAG GGCTGGGCTCTGGGCCTAAAGCTTTCCTGGGAAAGCTGATTGGGCTGGGCTGAGTGGTAT CCTCAGCCCCTAGGGCTCAGCAGGCATCTTGTGTATTCACCCTCTAATTTGGGTTTCTCC AGGGAACAGGCACGGTCTCCTGGTACCCAACAATACCACCGACCAGGAGCTGCAACACAT TCGCAACAGCCTCCCAGACACAGTGCAGATTAGGCGGGTGGAGGAGCGGCTCTCAGCCTT GGGCAATGTCACCACCTGCAATGACTACGTGGCCTTGGTCCACCCAGACTTGGACAGGGT GAGGCAGCCCAACTTGACCCAAGAGTCACAGGGCCATCCTAGTCAGTGGTTAGCCACTGT TCTTTCCCAACAGGCAGCAATTAGGGGTCTCTCCTGTGGTTTTTCTATATGGGCTCTTGA GTTTCAGGTACTCATTGGAATAGTGATAACAGAGGCCTTATCAAGTGTCAGAAAGAAGCT GGGGAGGGTATGAATCCTTCATGATTGGGGAGATTGAACCATCCAGTCCTGCATCCTGGG CCAGGATAGGTGATTGACTGTTGAACTTTTGACTGTGGGTGAGAGGGGAAAGAAGTGATA TTGAGACCAGCCTCCAGCTGTTCAGGGCATGCATGAATATTAGGGGCTTCACAGCTGCCC TTGACTCTGCTCTAAGCTGTACTTCCTCCTTTCTCTGGGTGAGGCTTTCATATGAGGTAC AGAGGAGAAATGAGGGGCTCAGGGAGCCAAGGCCTGGATGCTTCTGGGCATGGAGAACCT TGGTTCTGGGGCTGTAAGTTCTGAGCCCTGAACACAATATCTTTGATTGACAGGAGACAG AAGAAATTCTGGCAGATGTGCTCAAGGTGGAAGTCTTCAGACAGACAGTGGCCGACCAGG TGCTAGTAGGAAGCTACTGTGTCTTCAGCAATCAGGGAGGGCTGGTGCATCCCAAGACTT CAATTGAAGACCAGGATGAGCTGTCCTCTCTTCTTCAAGTCCCCCTTGTGGTAAGCATTC CTGTCCTCTGAACCCCGTCTCCCGAGGCAGATCCTTTTGCCTAGTGTTTGGGAGTCTGGG TCATTACCTGCCACAGTTTGGGACTGGGGCTGCAGGTCAGGGAGGAGCAGGGTTTGGGGA GAGTCTTCATTGAGGAGGGAGAGAATTTGGTGCCGTGACTCACATTGAGCCCATCCCTTG GCAGGCGGGGACTGTGAACCGAGGCAGTGAGGTGATTGCTGCTGGGATGGTGGTGAATGA CTGGTGTGCCTTCTGTGGCCTGGACACAACCAGCACAGAGCTGTCAGTGGTGGAGAGTGT CTTCAAGCTGAATGAAGCCCAGCCTAGCACCATTGCCACCAGCATGCGGGATTCCCTCAT TGACAGGTACCTGGGGCCTCTCCTTTCTTCTGCTCAGGGTTGGGGGTTAACTTGCATTTT GAGAGTATGGGGAAAAGATGTCATCTAGAATGGGAGCCTACCAGTTTGTTCTGGTAGCTT CTCGAGTGTGAGAGCATATCTGTACACTGCTGAGCAGATAAGAGCCAGCATATTCAAAAA ATATTTCTTGAGCATCTGCTAATCCTCATCTTTGTGGTTTTTCAGGGCTAGGATACTAGA GCAGTAGCTGCTTGAGCAGCTTGTCAGAGCTGGTCCCGGGATGAGGGCTGAGGCAGGCAC CTCACTTGAGAGTGAGGTGGGCTCTGTGAAACAGCTACTGACCGTGCGCTTTCCTTTCTC TTCAGCCTCACCTGAGTCACCTTCCAAGTTGTTCCATGGGCTCCTGGCTCTGGACTGTGG CCAACCTTCTCCACATTCCGCCCAATCTGTACCGGATGCTGGCAGGGAGGTGGCAGAGAG CTCACTGGGACTGAGGGGCTGGGCACCCAACCCTTTTCCACCTGTGCTTATCGCCTGGAT CTATCATTACTGCAAAAACCTGCTCTGTTGTGCTGGCTGGCAGGCCCTGTGGCTGCTGGC TGAGGGTTCTGCTGTCCTGTGCCACCCCATTAAAGTGCAGTTCCCTCCGG OMIM ID 602912