Entrez gene ID | | 3710 |
Official gene symbol | | ITPR3 |
Full name | | inositol 1,4,5-triphosphate receptor, type 3 |
Aliases | | ,FLJ36205,IP3R,IP3R3, |
Gene summary | | This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p21 |
Gene position | | 33589161 - 33664351 Map Viewer |
Gene orientation | | plus |
Gene size | | 75191 bp |
Gene sequence |
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OMIM ID | | 147267 |
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