Entrez gene ID | | 373 |
Official gene symbol | | TRIM23 |
Full name | | tripartite motif-containing 23 |
Aliases | | ,ARD1,ARFD1,RNF46, |
Gene summary | | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q12.3 |
Gene position | | 64920187 - 64885507 Map Viewer |
Gene orientation | | minus |
Gene size | | 34681 bp |
Gene sequence |
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OMIM ID | | 601747 |
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