Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRIM23 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID373
Official gene symbolTRIM23
Full nametripartite motif-containing 23
Aliases,ARD1,ARFD1,RNF46,
Gene summaryThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q12.3
Gene position64920187 - 64885507  Map Viewer
Gene orientationminus
Gene size34681 bp
Gene sequence
OMIM ID601747