Entrez gene ID | | 3735 |
Official gene symbol | | KARS |
Full name | | lysyl-tRNA synthetase |
Aliases | | ,KARS2,KIAA0070,KRS, |
Gene summary | | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16q23-q24 |
Gene position | | 75681585 - 75661622 Map Viewer |
Gene orientation | | minus |
Gene size | | 19964 bp |
Gene sequence |
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OMIM ID | | 601421 |
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