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Gene information for KARS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3735
Official gene symbolKARS
Full namelysyl-tRNA synthetase
Aliases,KARS2,KIAA0070,KRS,
Gene summaryAminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q23-q24
Gene position75681585 - 75661622  Map Viewer
Gene orientationminus
Gene size19964 bp
Gene sequence
OMIM ID601421