| Entrez gene ID | | 375 |
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| Official gene symbol | | ARF1 |
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| Full name | | ADP-ribosylation factor 1 |
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| Aliases | | ,-, |
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| Gene summary | | ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 1 Locus: 1q42 |
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| Gene position | | 228270361 - 228286913 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 16553 bp |
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| Gene sequence |
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