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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KCNH1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3756
Official gene symbolKCNH1
Full namepotassium voltage-gated channel, subfamily H (eag-related), member 1
Aliases,EAG,EAG1,Kv10.1,MGC142269,h-eag,
Gene summaryVoltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q32-q41
Gene position211307457 - 210851657  Map Viewer
Gene orientationminus
Gene size455801 bp
Gene sequence
OMIM ID603305