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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KCNJ4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3761
Official gene symbolKCNJ4
Full namepotassium inwardly-rectifying channel, subfamily J, member 4
Aliases,HIR,HIRK2,HRK1,IRK-3,IRK3,Kir2.3,MGC142066,MGC142068,
Gene summarySeveral different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q13.1
Gene position38851203 - 38822332  Map Viewer
Gene orientationminus
Gene size28872 bp
Gene sequence
OMIM ID600504