Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KCNN2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3781
Official gene symbolKCNN2
Full namepotassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Aliases,KCa2.2,SK2,SKCA2,hSK2,
Gene summaryAction potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q22.3
Gene position113698016 - 113832197  Map Viewer
Gene orientationplus
Gene size134182 bp
Gene sequence
OMIM ID605879