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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KISS1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3814 Official gene symbol KISS1 Full name KiSS-1 metastasis-suppressor Aliases ,KiSS-1,METASTIN,MGC39258, Gene summary This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq] Location Chromosome: 1   Locus: 1q32 Gene position 204165619 - 204159469  Map Viewer Gene orientation minus Gene size 6151 bp Gene sequence >KISS1:complement(55648111..55654261):Length=6151 GAGAACTCTTGAGACCGGGAGCCCAGCTGCCCACCCTCTGGACATTCACCCAGCCAGGTG GTCTCGTCACCTCAGAGGCTCCGCCAGACTCCTGCCCAGGCCAGGACTGAGGCAAGGTAG GCACACTGCAGTGTCCACCCCTGGGAAGGGGGTCTGCCCTGACCTGGGGATGCTCTGGAG GGGAGCAGGGAATCCGTTCTAAGACGGACAGATGCATCCAGGCAGGCAAAGGCAGGGGAG GGAGACACTGATCTTTCCTGTTTACCAGCCTGGCCAGATTATCCTGGGATGCCTGGGCGA ATACACTGAGTCGCACTTTATTTGTGAAGCTAACACTCTGGGGATCCCGAGGGCTCTCTC TTGCTGTGGAAGGAATACATGCAATAAATAAATGCTGTGGCTGGAATTAGAGACCACAGA CACGCTTGGATGGACCTAGGGAACCGCTCGGGGCTCTTGAGAGCAATGGGGCTCCTCTGA GCAGCTCCCCCCAAATTACAGATGGCAAATACAAGCCTAACCAAGGGCATCTACCTACCC ACTAAGAACTAGGGGCCACTTCACTCCAGAAGCTTTCCAACCATGCCTGGAATTTCTGTC ACTCACTGGATACAAACCCCCCAGGGTGGAGGGAACCACAAAAATTGTCTACAGCAGGTC GGCCACTCATGGCCCCTTTCCAAATAATTCATTTCTACCATATATGTTAAGTGCCCCGAT GGGCTGGGCAGTGGAATCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGATAT GTGTGTATGGGTGTATGTGTGTATATGTGTGTGATGTGTGTGCGCATGTGTGGTGTATGT GGTGTATGTGTGTGTATGATGTACGTGTATGGGTGTATGTGTGTATATGTGTGTGGCGTG TGTGTGCATCTGTGGTGTGTAGTGTATGTGTACGGGTGTATGGGTATATATCTGTGTGGT GTGTGTGCATGTGTGGTATGTGTGGTGTATGTGTGTGTATGATGTGTATGTATGGATGTG TGTATGTGTGTGTGTATGTTGTGTGTATGGGTGTATGTGTGTATATGTGTGTGTGGTGTG TGTGCGTGTGTGGTGTGTGTGCATGATGTGTGTGTATAGGTGTATGTGTGTATATGTGTG TGGTGTGTATGCGTGTGTGGTGTGTGTGGCATATGTGTATGTGTGTGTATGGGTGTATGT GTGTGGTGTGTGTGGTGTATGTGTGTGTGTATGATGTGTGTGTATGGGTGTATGCGTGTA TATGTGTATGGGTGTGTGCGTATATATGTGTGTGGTGTGTGTGTGCATGTGTGGTGTGTG TGGTGTATGTGTGTGGTGTGGGGGGTGTGTGTGTGTGTGCTGGGGTCAGGCAGAGTTGTC CCATGGCGCACATGGTAAGTGCCATCCACAGTGGGAAGGAGGCACTCGGGGGGAAAGGGG AGCCGGAAGAAAGAGTACCACCCTCCAACCACACAAGCCCACTGCCCTCCTTCCTGGCCC ACCACCCTGCTTCCGCACAGAGAACCGGAAATGTACATCTACCCACATTCCTGTCTGGCT CAGACCCCTCCAGGATGAAGCCCCTGCAGGGCCCCTTCCCCCAGCCTTGTCACTAGCTTT CTCTCCATGCAAAGCTCCATCCTCTTGTCTAGCTAGAGGGCCTGAAGTTCCCTTTGCACT CAGCCCCTGCCCTTGCTTCAGCGCCTTAGCACCGTCCTGGGAACACTTTCTGTAAACCTT TCAGCGATTCATGCTCAGAAACAGCTCAAGTGCCACCCCCTGCCAAAAATCTGCCTGGTC CTCCTAGGTTGGGTTCCCCTGGACTCCCATATCCCCTTGTGGATTCACATGCATCCGGTA TGTCATTTACAGTGTTATTTTGAAATGATCTGCTGATGAGTTAATTTCTCATGCTAGACT TGAGATCTTGGGGGCAGCAACTCTGTCTTAGCACACCTGTGCACCCCTAGCACCTAGCAC AGCACCAGCACCTAGTCGGTGCTCAAGGAGTGATTTCCAAATCAACCCAGACCCTGTGCA TCCACGGTCTGAAATGCTTTTACACTATTCTCTCCAATGGATTAATCCTACCTCTACTCC GTGCCCCAGCCCTGGGCCTTAAGGTAAATGCAGAAAGCTGTGGTCTGGGTTTCAACTTGT CACAGTATCAAAGTCTGCAAGGATAAGTAAACTTCTGAGCAGGTGGCTGGTGGCCAATCT GATCCAGGGTTCTTATTTTATAGATGGACCAATGAGGTCTGGAGATGGGGGTGACTTGCT CACATTTCACAGGGAATGAAAGCAGAGCTGGGGCAAGATTCAAGTACTCCTCATTCCATT TCAGGGTTCTTACTCTTTACTCCATGCCTGAGTCCTGCAGGGAGCTGGGTGAGGAATGGG GGGTGGGGGTGTGGGTGCAAGAGCAGAGAGATGCATGGGCCTGAGCCACCATTAGGAGCT GATGGGCACAAAAGGTTCTCATCCCCCAGTCCCCCTTCCCCAGGGAGAGCGGCTCCAGGC TGTGGGTCAGGCCAGGACAATCTTTTTGCTCAGCTGGCATTGCTCCTGCCTCCCCAGCCT TTTGTCTTTAATCGTGTTTGTTGGACAGTCTCAAAGTGTCTGGTGACTTTTTCAAAAAGA AATTAGATTTGGGAGCCGGAAGAGGTAGGGTGGGGTATGTGGGGTGTCGGTGGGGCAGAG CAAGGCAGGGTGATGGGAAATGGTGTGAGGATCAGGGCACACGGCTCCCATCTCAGCAGC CAAAATGATGAGGCCAATTCAATTCATAGCCTCTTAGAGTCCACAAAGAATAGACTATGG AGATAACTGACCTGATAAATCAAGGAAAGGTTTTTCTTTTCCATGAATGATAGGCAATAA GACAATTTAATGACCGTCTTCAAGGCTGTGAAGGGCTATGAGAGAGAGCAAGATGATTGC CTCTTTCTTTCTTTTTCCTTATAAAAGAAAAAGAAATAAGTTTCTCTTACAGCAGGAGAG AACAAGGTCAGACTCAAGCGTATGGATGGGGAGAGTGGAACACAGAAAGTTGTGGATTTG TGCAGAACCCACCATGGAAGGAAGAAGTGCCTGTTGCCAGGCTCCCGAGAGAATATTGGA ACCTCAAAGTTCCCCACTCAGTGCCCTGAAGTCCTTGCCCTACTTCACCCCTCCCCAGTC ACTCCTATATATGGCATCTCACCCCACCTTTCTCAAACATTCCTCTCAAGCAACCCTGAG ATTCAGAATCCTGGCCATTCTCTGACCCAAGCAGTCCTGCCCCTTCCACCAAATTGGGTC TTTCCTTTTTTCCTAACTTTACTGTCCTCACCTCCTCCAGGAAGCCCTCCCTGATGACCC TCACCTAGCATGAATTCAGCTTTAACTACACTGTGTAAAGAGTCTCAATCCCATTTCACT GATATATTTGTTTAGACTCATCCCTCTACCAGGAGCCTCCAAAGGCAAGAACTTGCCCCT CTCTTGGAGGACTGTCCCTTTTGCACTGGGCTCTGCCCTCAGCACCCAGCCCAGATCCTG TGCCTGACCTAGTCTTTGTTCCCTCTCTCTGTCTCAGCCTCAAGGCACTTCTAGGACCTG CCTCTTCTCACCAAGATGAACTCACTGGTTTCTTGGCAGCTACTGCTTTTCCTCTGTGCC ACCCACTTTGGGGAGCCATTAGAAAAGGTGGCCTCTGTGGGGAATTCTAGACCCACAGGT ATGTATCCTCTGGGGAAAGGAGTGGGAGGGAGCAAGTGGGTTGTTGCAAAATGAGCTTTC CCGTATTTTCCATCTAGTCGACTGGTGTGAGTTTAACATTGCATTTGGTGGAAATCTAAG ACTGGCACACATGCAACTCATTGAGGGGGTCCTGTTAACCCTGCAAGTGACGGATGCCTT GCCTCTGTGATGGCCTCAGTCCGCCCACCTAGGTTCCAGGGCTTATTAACCCTTGAGCTC TTTCATGGTTTCCTCACACTGTGTTCTCTGCTCTACGTCAGCAACCTCTCTGTGCCGATG TTGAGAAGAAACTTCATATGCAACCTTGCTTTATCGGTGACCTCAGATTCTTTGTGGAGA ATTTGGAAAAAAAAAAAAACCTAAACCAAAGGGCAGATATTTGATACCTATTAACCTTTT GGAGACAATGAACTGTCTCCAGTTCATTGGGGAACTGATAAGCTGGAAAATTTGAGACCC ACAGAGGTAAAGAGATTTCCCCAGAGTCGCTCAAACACTGTGGAAACCCAGCAGGTGTCA GAGCTCCCCAGGAGTGTGTCTGGTGAGTGGCACAAGCTAGAACAATACTAGTCCCCAAGT CAGGAGCTGTGGCTTGGCACACTTCCTGGTGTCAGCTTTCTGGGCAAACTAGAACCCATG ACTTAGCTTCTCTGGACCTGAGTTCCCCCAGCTATAAAACTTGGGGCATGCCCTCTACAC ATTTGATGTCATCGTATATGCCCATAAGACCTTCCAGAGCACAGAGGACACGGCCCCGGG TGTCGTTTGCCAAGCGTGTCTTCTGTCCTGGGATCAGGCGTTTTTCTGGGTGAGGGAGGC TACCCCAGAAAATAACCCCACACTGCCCAGGGATATAGGGTTGTTGGCTCTTTTTGGCAA AAGGCTTTAGGTGAGGTCACCAACAGCAGCCTGAACAGTGATTTACTACTGGTCTAGCGT GCGCAACTGGGGAGGAAGCCATCCTCCTCCTACCTCAGCCAGGCCCTGGGCAAGGGCTGA GGGACCTCGCAGGCGACTGCCATTAACTCTGGACCAGGTCCACACTCCTCTTTTCCAGAC TGTGCCAGGGCACGGAGGAGCAGGGCTCAAAGCCAACTGCCGCCCCAGCACATCTATTCA CACCCATTCACACACCAGGCCTCATTTCCACTAATCTCTTGCCGCAATGGGCTGGGGTTA TTGTCTACACAGAGCTAGTTGCCCTATTTTACAGCCAAAAAGTACAGTGAACTTAATGAG CCTTGCATGTGAAGTGCCTTCCAAATTAGCCTTGTTAATCCTCAGAATGAAGGAGAGAAG TTATACCCAGGATGGAGGAAGAGAGCCAGTTAAGGTGACCTAGATAATTTTTGTTTCTCA TTGAGTCCTTATGTAGCTTATTGGGCGGGGTTGGGGGGGTGGGTGGTCACAATTCTTATC AAAGACGAGTGTTGGAACACAGGTGTGTGGGGCCACAATGTCTTAGCTCCACTTTCTCGA TTTCTGTTACTACACGTTTTTAGCTTTTATGTATTTAACAGGCATTTATTGAGGCCCCAC TATGAGCAAGCCACTGTTTCAAGCACTATGAGAGATACAGAGATGAATTAACATGGCCCC ACTGCCCAGGCTGCTCACAGCCAGGAAGGGGCCCAGAGCTGGGTGTTCAGCAAATACTTT GGTTTTCTTTATTTCCATGCCCTACCCTGTTTGTTTCCTAAAAGGAAGTAACGTAATATG AGAGTTATTTAAGATAATTCTGGCAAACATTCTAAATCAAAGCTATGTTGGAAGAGGGAG GCGCCTAGGGCCTAATCATCCCAGCTAAGGTGATCGTGCTGGTTCGCATGGCACTGAGCT CCGAGCTTCCAAAAGGTCAAGGAAGGAAAAGAAGGATAGGATGGGATGACAGGAGGTGTT GCAAAGCCATCTTTCCCGGACCCCGGCCTCATCTTTCTGTGCCCTCTGTCCTAGGCCAGC AGCTAGAATCCCTGGGCCTCCTGGCCCCCGGGGAGCAGAGCCTGCCGTGCACCGAGAGGA AGCCAGCTGCTACTGCCAGGCTGAGCCGTCGGGGGACCTCGCTGTCCCCGCCCCCCGAGA GCTCCGGGAGCCCCCAGCAGCCGGGCCTGTCCGCCCCCCACAGCCGCCAGATCCCCGCAC CCCAGGGCGCGGTGCTGGTGCAGCGGGAGAAGGACCTGCCGAACTACAACTGGAACTCCT TCGGCCTGCGCTTCGGCAAGCGGGAGGCGGCACCAGGGAACCACGGCAGAAGCGCTGGGC GGGGCTGAGGGCGCAGGTGCGGGGCAGTGAACTTCAGACCCCAAAGGAGTCAGAGCATGC GGGGCGGGGGCGGGGGGCGGGGACGTAGGGCTAAGGGAGGGGGCGCTGGAGCTTCCAACC CGAGGCAATAAAAGAAATGTTGCGTAACTCA OMIM ID 603286