Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KLRC1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3821 Official gene symbol KLRC1 Full name killer cell lectin-like receptor subfamily C, member 1 Aliases ,CD159A,MGC13374,MGC59791,NKG2,NKG2A, Gene summary Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq] Location Chromosome: 12   Locus: 12p13 Gene position 10607215 - 10598627  Map Viewer Gene orientation minus Gene size 8589 bp Gene sequence >KLRC1:complement(3358751..3367339):Length=8589 GCATGCCCCAGAGGTACAGATGTATATGTCTCCCAGGAAGTCTCTGTGGGTGAAGGACTG ATCTCAAGTTGTGGCTGACACTAGTTAAAGCCAAGTTAGAGGGCTGTTTCAGGGTCTACA TTGAGACTACAGTTGATATGCCTACCTCCTGAGACACTAGTGTGTGAGTCTCCTCCTGGG CCCCTGGGCAAATGGTTTTGGCAGCATGACCAAGGCCTAAATGGGGCTGAAGGCAAGCAC AGGAGGATGGGTCCCTTTTCAGGTCTGGAGATGGAATCACTGTTGGTAAGTCTGCCACTT GGATGCAAATCTATTCCCTAAAACAACCTTCCTAGGTCTTGGGTTCCACTGGCATTTTAC AAACTCCTACTTGAATTCCAAACTCCCTCAAAGGAACTTTTGTCTGTGGATGGCTGAAAA ATTATTGTTGCTGTGGGGGCATATGTGTGGGGGACCACCTATTCTGCCAATTTACTGACT TTCCTCCTAGTAAGATTTTAAAATTACTTTTTCCCCATACATAGTTTGACTTCAGTTTTT GTCATTTACAACTAAATATTTCTATGAAAGTCGACATAATTTGTTATGGCGGAGGATGAA TAAATGAAGAATGTAATGAATAGCTATTTAATATTTCAATTTCTGGTATGCTAATATATT TCAAAATTGATTAATATTTTACCTATCCAAGATATTTTTATCAAGGGTAATCTGAAGATT AAATAATCTATTTTTAAAAATTAAGTGCAAAAATTTAAGAACTAAGAGAAGTTAATAATA TAACTTTGGCAATGATGCTTTTTGTGCCAGCTACAATCAATTGAGTAATTACTGCAGTAA TTTTTCAGAATAATTAAGGAAAAAATCAGTAGATATCAGTTGATAATATTACTATGAGTT TTAGAATGTTTTCTATTATAATGGAAGTGACATAATAAAATAATATAAAGAAAAGAAGTA TGCAATGTTAAGATTTAGCAACCTAGTCTAAAAGGCACTCTTAACAAGGTGAGGGTTGAC AATGTTCGTGATCAAGACAGAAAAAAAAAAAATTCTCATAGGCACTTGAAAAATGAACCA ACTAAATGACACACTTTCAAAGTCAACCTTGTACTTTTAATAGACCAAGTATCCTATATT TTGGAGGTGTGTGATGAGATAAAACTGATTTCACAATAGCCCATGTGTAGAATTTCCTGT TCAAACCTTAGTAACACGTTGATGAGAAATCTACTTTTTCCACTCTTGACTCACTCTGAG CCTTCACAGGGCAGTCTGCGAAGATTGCAGGCATTGTTTGTTCTTGTCTTGGATTTATGC CTTTAAATTTCACCTTTTATTACACAGCTATAGCAGGCCTTTTTATGAGACTAACCTGGC CTCTCCACTAAAGGATGTGTGACTTTCTGGGGACAGAAGGTATGTATTGCTACTCTCCAA CTCTCTACTAGCCTACCTCATTTAGTGGGTGATTTCAAGTGCTCAATATGATACAAAGGA GGTATAATTAATATACAATAAAATCAAAGTAGAATATTGCTGTCTTCATTTGAATAACTC AGGGTAAAAACCTAAAATATGAAATATGTTGAAGGATTTCTTAAAGTTTTCAAATTATTG TTTGTGGAAATCTAGTGGGTTTGTTGATCAATATCGTTTAAGGGAAAGCTATTAACATCA CAATAATGAACAATTAATTTTGTATTTTGTAATCAGTACATCATGTATCTTTGAATAATA ATTTATATTTAGCTTAGCCATTAAAGATTATTAAAATAAATCAATCAATTGATGAAAGCC AAATACAATTCCTCAGACACGTAGATTAGAGAAAAGCAGTTTTTATTTTTAATAAAAATC AGAATGAGGTAGATTACATAAAATGCTAAAGGTATTACAAAGCAATAAAAATACTTTTTA AAAATTGATCAAAATATTGCAAAAAAAGATGTAGCGCATGGACATAGGAGACTTATCTGA AGATTTATTTTCCATGCTTTAACTGACATGAATCAGAAACAGTAACATAACAATTGTGAC TAAAATAATAATTAAAGTAGCTAATGCTTATTGAGAACTTTAAGTGCCAGGTTGAGTGGT AAATGTTTTACATGCAACGTTTTATATGTTCTTATGCCCATTTTAGATTAACAAACTGGG TTATTAAAAATAGAATAACTTTTTAAAGGTCGCACATTATAAGTGTCAAAGCTAGAATTA ATTCTAGATCTCACTGACTCCAGAGCCCATTGACTAAATGATTTAATTACATTATCTGAA ATTTTACAAGTACTTATACAACTAAAGTGGCCTTTACTCACTTTGACAACCATAAAATCA TTCTATAAGTTTAAATGAAATGTGCTTTAACATGAATTACCTATACTTTTATTTATCATT TTTTGGTTCATAATTTAGCCAGGAAATAAATTACCAATTACTAATTAAATTACCAATACT TCTGTAAGTATTAACAATTTATGTAGTGTTCCTAATACTATTTAGGTTATGCATAAGTTA ACTGTGTCACATAGCATTTTCTGTCATATACAAATATTTAATTTTTTATAATTTTTAATA AATAATTTTTAATAATTTCTTAGAACATTTCAGCCATTAAGAAAAGACCATTTAATTACC TCTATTGATTTTCATTAATGTGTATAAATTACTAATTAAAAGTAATGTAGTGCAAGAAAT TTTTATATATATATATGTCAACTTTACTATTACTCATGTGCAGACCACATAGTCTTAACC ATTACTGGATTTCAAAATTAACATAAAAATGAGTGCAGAAGTTTTTCTAATACAACATTT TAATTTTTAACACAGGTAAAACATCAGACTTTAAGAAATATATTTTTATTCCTGAACTTC TTTATTCCTTAGTAATTTATTGCTTCTCATTGCCCCAGCAATAATATTTTGTCAAATGCA GAAAATTTATCTTTTTTTTTTGAGTCGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAG TGGCACAATCTCCGCTCACTGCAACCTCTGCCGCCCATGTTCAAGAGATTCTCCTGCCTC AGCCTCCCGAGTAGCTAGGACTACAGGCGCCTGACATCATGCCCGACTACTTTTTGTATT TTTAGTAGAGACGGAGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTG ATCGGCATGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGC CTAAAAATCTTTTTTTAAAACAAATATTCATAAGAAACGTGTTTAGGCTTGAAGAAAATC AGAGAAAGAACTTTAGATTATTTAATGCAAAATGAGCTCCAATACTCGTTCTCCACCTCA CCCTTTTAATTGCACTAGGGAATCCTGTATATAAACCATTTATTAACTTCTTAACTACTG TTATTATAGAGTACAGTCCCTGACATCACACACTGCAGAGATGGATAACCAAGGAGTAAT CTACTCAGACCTGAATCTGCCCCCAAACCCAAAGAGGCAGCAACGAAAACCTAAAGGCAA TAAAAACTCCATTTTAGCAACTGAACAGGAAATAACCTATGCGGAATTAAACCTTCAAAA AGCTTCTCAGGATTTTCAAGGGAATGACAAAACCTATCACTGCAAAGGTAAAGCATTTAA AAGATCCTCAATATAACAGTCTAGGATGTGCAGCTTGGGGTACAGGAATGTGGGGAAAGA GAAGGGAGTGCTCATATATCTTCTATTTGCAAAGATCAGAATTCCAAGTTGAGATATGCT ATTTCAATGTAAAGTATGAAGACTGATTGAACTCATTGTTGAAGTTTGTAGTCTTTGTCA AATAATTCATGGAGCATTATTTTTCCTGAAAATTCAATGGTATATTATTCTGAGAAAAAG ATTACAATGGGAGATGAGGGTTTGGGGTCCAAGTTTCTCTGTATGATTCCTGTGCATTCA GGTTCTCTTGTCTGTGAATCTTCTAAACGACTGTATCCACCTCTCCTTTCGCACTGTTCC CATTTCTCTCCCTGCAGATTTACCATCAGCTCCAGAGAAGCTCATTGTTGGGATCCTGGG AATTATCTGTCTTATCTTAATGGCCTCTGTGGTAACGATAGTTGTTATTCCCTGTAAGTC TATTTTCGAAGATTACAAGGGGAATTTTCACGTTAATGATTGAATGTGCCTCTAAACATT TCATATTTTCAGGGAATAGAGTTCTCATTGTAATGTATATATTTGGACTAAATGTGGAAT GATTATTCTGAATTTGTCAAAGAATAAATGAAAGAATAATTGTTGAAAGTATTCGCTTCT GATGCAATCGTATGTATATATTTGGATTTCATAACTCAAAAATATGTTCTAGGAGTCTGA AAAACCTTACTGAGAAATAGAAATTAATTTTTGAAAGTAGTTAAATCAAGAATTATAAGA ACTATATGAGATGGTGAAATTTGGTTCTTTAGATCTATGAAATACTTTTCCAAAAAACCA CCATTACTTTATCAAATTTTTCTTAAAATCAATTTTATTCCATATTATTCTAACTCTAAA TAATACAAAAAAATTCAAACAAAAACTTAAAATTATTATGATTGATTTAGATGCTAATTT TTTTACAAAGATTACTTTAATTTTTCTAGCTACATTAATACAGAGGCACAACAATTCTTC CCTGAATACAAGAACTCAGAAAGGTATATAATAATTTTTAAAGTTTTAATATTGTACAGT TTATTTTTTCTTGATCTTAGGCTGTACAAAAATAAAATTTTGGGTGAAAAATTATAAAAT TTGGCAATAAGTGTTCATAAATAAAATTAGAGTAAGGCATTCACTTGTCATCAACTATAA GTAAAATCACTATGCTTTCTTTTTATCTGTTGTGTTCAAATTCTTACTGCTATAATATGA TAAGATACAAGTTATTTATTGTTCCTTAAAAATCAGATTAGTTCATTGATTTTTCAAGAC ATGTATAGAGTGGATTTTTGTTTGCTGGTTTGCTTTATATGGGAACACAATTAGGAGATG AAAGGCTGACCCTTTATTGCGCATGTGTGTATAAGTGACTGGGTATTTTGACACTATATA TTTACCAGCCCATGAAGATGTATAGATATGTTGCATACGTATAGGTTTATATGTTTGCAA ATATGTGAACTAATTTTCATTTTTAAAAATTCATATTGGTCTAGATAGTAATTCATATCT TTATTTAGCACGTCATTGTGGCCATTGTCCTGAGGAGTGGATTACATATTCCAACAGTTG TTACTACATTGGTAAGGAAAGAAGAACTTGGGAAGAGAGTTTGCTGGCCTGTACTTCGAA GAACTCCAGTCTGCTTTCTATAGATAATGAAGAAGAAATGGTAAGATGTAAATGTTTTAA ACACTTTATGAAAAGCTTCTTTCGGTCGATAATATATTTGTAGAAATCATCCATATGTGT GGGTATATACATTTAGCTTATATGTTTTCAAGTTTATGTAGTATTTAATTGATTGACTTA ATAATGTTTTAAAATTCATATACTGCTAATGTACTTTTGATTATTTTCAGTTTTTGCTTT TCATGGAAAACCATGCTTCTAGAAATGCTTTCAATCCACAATACATTTTGCTATCTAATT TTATCGGGCATGATGTGATCTGGTCATGCAGATTGATCACAAAGTGAATGAACTCCTGTG ATACAAGTCAGATCATGAAATAAAAGTTTCCAGCTCTAGTAGTTCCACCCCTGTGTATGC CCTCATCACTTATCCTGACTCCTCTCCAAAACACTGTCTTGACTTTTAATGTTATAAATA ACGTTTACCTGCTTTTGAATTTATATAAAGGGAATCATACACTGTGAATTTCATGTCTGT GTTTTTCACTCCTATCTGATATTTATGCAATTCCTCCATATTATTGCGGTTATCTGTCGT TTATTACTGTTCACTGCTGTAGTATGTACAAAGAACACTAAGAATCCATTCAATCCTGTG TCTCTGGATGGGGAAGTGAGTCTCATGCCCTCAGGGACAAAGAGGACCCTGGGTGGTGCA CTGGTAGTCATTGGGTTCCTTTGCTGATCCTCCTCACCCACATCCACTCTGGTGTCTCTT GGTATGAGAAGGAAGTACTTCCTCTGGCTGTATTGGTAGCAAGTCTCCTGGTAGATCATC CTTGCCAGTGGTACCAGCCTTGCCTGTTGTTGCGGAGGGGACTCCCCTTCAATACAGAAC AGGAGTGAGCTTTGCTGGGCCTCCTCCTATTGCCAGGTTGGGTGTAGGGAAACAGCAGGC CTAGGTCACCTTCTTCTGTCGTGTGGAGGACTTAACATGCTCGCTCGGACACTTGGTTGA TCCCTGATGCTAGGGTCCCAGACAATTTCATCTTTCTCTTTCCACCTTTCAGAGTTCTCC ATTGCTTTTGTCTTTCATTAATCCCAGAGTTTATAGTTGTTTTTAGTAGGGAGTAGCAGA GAGAGACGAGTCTACACCACCTGGTCAGGATCACTGTTATTCCACCAAAACCAAATCAGA TAAAAAAGTGAGGGCTTATCTAGTTAAAGAATGGTGTGGTACCCAGAAAACCCAATATGT AGCTTCCATGTCATTTATTTCTGAATCACAACCTCTAATTTCTCTTCTAAATCTCCAACT CTGAGAAATATAGCACAAAAATAGTTTGATTTAGTCACAGTATCTGGAGGAATGAATGCA CAGTATCAGGAGACTTATTTAAATCCTTACTGTGTTTATTCAGTCAATTGGGGTAACTAT TATAATGCAAGAATTAAAACTTCTTTATTAACATGAGAAGAATAAAAGTACTAAGTATAA ACATTGACGGGTTCATTTATATCAAAATTATAAACATTTATGAAAGTTTTTGGCACTGCA AATAGTGGTTTTCAAATTTAATATATTGTTTTTGTAATGTTTTCATAATTATTATTTAAG TGAAAATTCTTTCTTTTCTTTTAGAAATTTCTGTCCATCATTTCACCATCCTCATGGATT GGTGTGTTTCGTAACAGCAGTCATCATCCATGGGTGACAATGAATGGTTTGGCTTTCAAA CATGAGTAAGTTGTTTTGTATGGCGCTATATAACAATATATATATAAAGGATAAATTCAG AAGAATAATATGAATAAATCTATGTGGAATCATAGAGATGAAGAAAGATGTGGAAAGTTA GTGAAATGCTGACATAAATATTTTACAATAGACCATAGTAGTCCATATATTTCAACCGCT CATTGGTCAGCTAGTAACCTTCTTGATTATCAGGTGTCCAATCTTTGGCTTCTGTGGGCC ACATTGGAAGAAGAAGAGTCTTGGGCCACACATAAAATACACTAACACTAACGATAGCTG ACGAGCAAAAAAAAGAAAAAAAAAATCACAGAATGTTTTAAGAAAGTTTACGTATATGTA TTGGGCCGCATTTGAAGCTGTCCTGGGTCACATGCGGCCCGTGGGCAGCGAGTTGGACAA GCTCGAGCTGGACTATCAGGGAATTGCAGTGCTTGTTTTTATTAAAAAGCCACACTTACT TTTTTTCTTAAGAATATCCTCAAAGCACAAGAGTAGTGCTGTTGGCATATTGCTATAATT TTGTTATTAGTAGTTATTGTTGTCAATCTCTTATTGTGCCTAATTTATAAATTAAATTTT ATCACAGTTATGAATGTGTAGAGAAAACATAATCTCTCTATAGGTTCTGCACTATCTGCC GTTTCAGGCATCCACTGGAATCTTGAAACATATCCCTCGTGGATGAAGGGGGACTACTCT GTTGAGTGTTCAGAATAATGACTCTTACTAATATTATGAAAAATTTAATTACCCTTTTCC ATGAAATTATTTTCTTACAGTACATGGAAAATGCTTTCGTCTCATGAATCATTTGCTTAA AATGTAACAGAATATGGATTTTTCTCCATTACAGGATAAAAGACTCAGATAATGCTGAAC TTAACTGTGCAGTGCTACAAGTAAATCGACTTAAATCAGCCCAGTGTGGATCTTCAATAA TATATCATTGTAAGCATAAGCTTTAGAGGTAAAGCGTTTGCATTTGCAGTGCATCAGATA AATTGTATATTTCTTAAAATAGAAATATATTATGATTGCATAAATCTTAAAATGAATTAT GTTATTTGCTCTAATAAGAAAATTCTAAATCAATTATTGAAACAGGATACACACAATTAC TAAAGTACAGACATCCTAGCATTTGTGTCGGGCTCATTTTGCTCAACATGGTATTTGTGG TTTTCAGCCTTTCTAAAAGTTGCATGTTATGTGAGTCAGCTTATAGGAAGTACCAAGAAC AGTCAAACCCATGGAGACAGAAAGTAGAATAGTGGTTGCCAATGTCTGAGGGAGGTTGAA ATAGGAGATGACCTCTAACTGATAGAACGTTACTTTGTGTCGTGATGAAAACTTTCTAAA TTTCAGTAGTGGTGATGGTTGTAACTCTGCGAATATACTAAACATCATTGATTTTTAATC ATTTTAAGTGCATGAAATGTATGCTTTGTACACGACACTTCAATAAAGCTATCCAGAAAA AAAAAAAAA OMIM ID 161555