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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KNG1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3827
Official gene symbolKNG1
Full namekininogen 1
Aliases,BDK,KNG,
Gene summaryThis gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
LocationChromosome: 3   Locus: 3q27
Gene position186435098 - 186462199  Map Viewer
Gene orientationplus
Gene size27102 bp
Gene sequence
OMIM ID612358