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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARG2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID384
Official gene symbolARG2
Full namearginase, type II
Aliases,-,
Gene summary Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q24.1-q24.3
Gene position68086579 - 68118437  Map Viewer
Gene orientationplus
Gene size31859 bp
Gene sequence