Entrez gene ID | | 3840 |
Official gene symbol | | KPNA4 |
Full name | | karyopherin alpha 4 (importin alpha 3) |
Aliases | | ,IPOA3,MGC12217,MGC26703,QIP1,SRP3, |
Gene summary | | The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q25.33 |
Gene position | | 160283376 - 160217962 Map Viewer |
Gene orientation | | minus |
Gene size | | 65415 bp |
Gene sequence |
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OMIM ID | | 602970 |