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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KRT6B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3854
Official gene symbolKRT6B
Full namekeratin 6B
Aliases,CK6B,K6B,KRTL1,PC2,
Gene summaryThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q12-q13
Gene position52845910 - 52840435  Map Viewer
Gene orientationminus
Gene size5476 bp
Gene sequence
OMIM ID148042