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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KRT8 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3856 Official gene symbol KRT8 Full name keratin 8 Aliases ,CARD2,CK8,CYK8,K2C8,K8,KO, Gene summary This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq] Location Chromosome: 12   Locus: 12q13 Gene position 53298868 - 53290971  Map Viewer Gene orientation minus Gene size 7898 bp Gene sequence >KRT8:complement(15434277..15442174):Length=7898 AAAAGGCCATTCCTGAGAGCTCTCCTCACCAAGAAGCAGCTTCTCCGCTCCTTCTAGGAT CTCCGCCTGGTTCGGCCCGCCTGCCTCCACTCCTGCCTCTACCATGTCCATCAGGGTGAC CCAGAAGTCCTACAAGGTGTCCACCTCTGGCCCCCGGGCCTTCAGCAGCCGCTCCTACAC GAGTGGGCCCGGTTCCCGCATCAGCTCCTCGAGCTTCTCCCGAGTGGGCAGCAGCAACTT TCGCGGTGGCCTGGGCGGCGGCTATGGTGGGGCCAGCGGCATGGGAGGCATCACCGCAGT TACGGTCAACCAGAGCCTGCTGAGCCCCCTTGTCCTGGAGGTGGACCCCAACATCCAGGC CGTGCGCACCCAGGAGAAGGAGCAGATCAAGACCCTCAACAACAAGTTTGCCTCCTTCAT AGACAAGGTGAGGGTCCCCCCTGCGTGGCTGACTGTGCCCGCAGCCCCTTTCTCCTGGTA GTCCCGGTCCCTATGCACATCTCCAGCCCCCAGCTGGCGTCCTGCTGGGCCTCACCCGCC CTGGCGACACTCTCCCTTCCATCCTCCGACTCACCCCTCCCGTGCACCTTGGTTTGGGCT GGGTGAGGGTGGGGAGAGGGTCTGGACAGCCGGGATGAATCCTGGGGCTTCCTTCTTCCC TTTTAAACTGGAGGGTCTTGGAAGAGAGAGACAACTTAAGGGTACAGCCTAGTTCCCACC ACCCCTCTCTACAAATCCCGTTCTTCCTCAGGTCATTCTGTCCCCAAATTATAAAAAATA ATAGCGGTTATTGTTCTCACCCCAACCCGAGTTCTGACCGTCTTTTAAGCTATCGCCCTG CGGCAGTCCCAGCTGTTCGGGGACTACCCTCCTCCAGGTTCGCCTCTTCGCCAGCACTAC CCCAAGGGCTCCCCAGTGGTGCCTTTGTGATTTTTTTTCTTTCTTTTCTTTTTTTTACAT AGGGGTTTGGTGTGATTCTAGCATTCTAGGAGAAGGAAGTGGGTGTCTCGGTTCAAACGG GCAAATATTGATTGAGGCCTTTGGCGCCCGGAGGCCTGAGTGCGGGGGTCACAGAATGAG TCATACCCCGGCCCCTGCGCCGGCAGCGTGGGCGGGGCCGAGGGCGGGGTGAGGGGCTGC GGGCAGCAGTCTCGGGACGCTCTCCTCCACCTGGCGGAGCTCGGCGTCGGGGGCGGTGTG GGTGGGGTGGGGTGGGGTGGGGTGGGCTGGGGTGGGGTGGAGGAGGCGCCAGGGCCTGGC CTCGGAAAGCCCATGCAGGATTCAAAGTCTGCGGGCGTGGGACGCCCCGCCCGGGGTTTA CGTCCTGTTAAGTTTATGGCTTCAGATAACGCGGTCGCCCACCAACGCCCCTCGCCCATT CAGCCCGTGTCCCTTTCTCGCGTCCTGTCCCTGCTCCGCCCCAGCGGCCTGGCTCCACTT TCACACAGCAGGAGCCAGGCCGGGTTTTGCAGCCCTGGGACTCCGCTGCCTGAGGGGCCC CGGGCCCCCGGCGGCCCCGAGGATTGGGCCCTTCACGCTGACTGGCTCCTGGGAGGCATT GTGGGAACGGGAGGAGGGAAATCCTGGGGCAGAGTAAGCCGGGAGGAACCGGAGCCCCAG GAACCCAGTGGTCGGGGGCCCTTGGCGCTCCAAGCGCCTGGACTTGACTTGTTGACTGCG TTTTGCTAGCCCTGGGGTCCTTATAGAGAGCAGCTAAGCATAGGCTTTGGAATCTGAATT CTTGGTTCGCACTGCTCTGCCGGTTCCTGGTTATGGACTCCCTTGCCAAGTCTTATTTCC TCATCTATAAAATGAATATGAGAGCCCCTAAATCCATATAGGCAAAAGTTTTTGCCTATT CAAACTTACATATGTAAAGAGTTCAGCAGTGCTTGGCCCACATTCCATTAGGATAAGATG TTATAATCACTTTTTTTTAAAAAATAATTTTGGGGCAGAATGACCTGGGGAAGAAAGCGA TTTGCAGAGAGTGGTGGAGGGAACTAGGCTGTACCCTTAAAAGATTTCTGTCCCCTCCAG TTTAGAAGGAGTTACAAGTTTTTTTGTTTGTTTGAGACAGAGTCTCACTCTGTCGCCCAG GCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCCGCTTCCTGGGTTCAAGCGA TTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAAGTGCGTGCCACCATGCCCGGTT AATTTTTGTATTATTTGTAGGGACAGGGTTTCAATATGTTGGCCAGGCTGGTCTCGAACT CCTGACTTCAAGAAATCCGCCTGCCTTGGCCACCCAAAGTGCTGGGATTACAAGCGTGAG CCTCCACGCCCGGCCTCTTTTTCAATCTTAACATCTTTAGAAAGGTTGGCTATTTTTGGC CGGGCGCGGTGGCTTACGCCTATAATCCCAGCACTTTGGGAGGCCAAGGCGGGCCAATCA CAAGGTCAGGAGTTCGAGACCATCCTGCCTAAGACGGTGAAACCCTGTCTCTACTAAAAA TACAAAAAAATTAGTGGGGCGTGGTGGCAGGCAGGTGCCTGTAGCCCCAGCTACTCGGGA GGCTGAGGCAGGGGCAGGAGAATGGCATGAACTTGGGAGGCGGAGCTTGCAGTGAGCTGA GATCTTGCCACTGCACTCCAGCCTGGGCGCCGGAGACTCCCAAAGAAAGCTTGGCTATTT TTATTGATGTGTAATATACAACCTATGTAAATGAAGTTAGGCCTATTGGTTTGCAAATGC AGCTTTAACATAATTACCTTACCTGTCTCCTTCCCCTACCCAATGCTGAGGGACATTGCT CCCCACCTCACCATCATGCCATGCTTTCTCCCCCTGGTCATAGGTGATCTTTCCAGAACA GCTAACCAGGTGCCTGGGGTCTGGAGACCTTACTGCTTGAGGAGTGAATTAAGAGAAAAG ACTGCTTGCTTTCCTCCAGACTTTGAGCCCTGGCCTGATGTAGACCTTTTTGCTCTCTCC TCCTTCGTATAGGTACGGTTCCTGGAGCAGCAGAACAAGATGCTGGAGACCAAGTGGAGC CTCCTGCAGCAGCAGAAGACGGCTCGAAGCAACATGGACAACATGTTCGAGAGCTACATC AACAACCTTAGGCGGCAGCTGGAGACTCTGGGCCAGGAGAAGCTGAAGCTGGAGGCGGAG CTTGGCAACATGCAGGGGCTGGTGGAGGACTTCAAGAACAAGTGAGCAACTCCCACCCTC CACCCAACTGAAGTCACCGTGCTCTCCTCCACCCCTTGGGACCTTGGGACTAAGTCCCCA TGGCCCTCTGTTGTGGGAAGTGCAGTCCTATCTAATTAGGGTGACCACCTGATGAGGTTT GCTCGGAACAGTCTGTGTTTATGCCCAGGTTCCTAGCACAATTGTTGATAGTACCCACCC CCTTTCAATCTCAACTGTCTGGATTTGAAGAACAAATTATGTGTCAATGTTGACATGGTA AACCTGAGACGGGAGAGATAGGCAGCCTGTGGGCCTCACTTTTGTACTTAACATTCTGGC CCCTCTTTAGTCTTGACCCTTGACCTCTAGCAAACTCTAGAAAGTTCTGTCTGAGGTCTC ATGTCAGGCCCTGCTGTTAACACTCTCAAGGTGTCCAATCCGATGTGTATTCATGGATTT GGAGAGAGATTTCCTGCTTCCCACGGGCTAAGGGAGGGGTGAGGGTGGAGAGGGCAGCTG GGGAAGGCAGAAGGACCAGCCTTCTCATATCCTGCATCTCTGTGAACTGAATTTTCCTGA TTTTCACAACGCCCCTGTCTCCCAAAAGACCAAGGGCAACCTCCCTTTTGCCTTCATCCT CTAATTGTAAGTCTTTTCCTCACAGGTATGAGGATGAGATCAATAAGCGTACAGAGATGG AGAACGAATTTGTCCTCATCAAGAAGGTGAGGGAGTCTCCCTTCTCCTATCTGGACACTG GAGGCTGGGGCTCAGAGACTCAGACCAAGAAGCTTTCTGGGTTTTGTCCCTAAATATTCC TAAGTAGTGGGACAAACTCATTTATGTAAACATTTGGGTGCACAGAAAGGTAGACAAGGA TGGAGTGGTAGGTGCATTTGGACAGAACTCTTGACATCGGTGTTGGGACATGGTTCAGAA AACAGAGCAGTAGAACTGGAGATCTGGCTCTAGAAGGCTCCCTAGAGAAGGAGGTGGAAG AGGGTGTGTTGCAGGAAGCAGAGGTGAAGGTGTGTGGGCTGAGAATGCACATGTGATGGG CAGAGGCTGGGCTGGAAGATCAATCCACAAAGTGGGCAACTAGAAAGTCCTGTGACCAGG CCATTGGGTGGACCTTGGGAGCCCCTTGGTTGGGGTTGGGTGTGGAAACCCAGCTCAGGC TCCCCTCTCCTCATCCCCCAGGATGTGGATGAAGCTTACATGAACAAGGTAGAGCTGGAG TCTCGCCTGGAAGGGCTGACCGACGAGATCAACTTCCTCAGGCAGCTATATGAAGAGGTA TGTTCCTGGTCGCAGGAGAGTGAGGGTCCCCCAGCCTTGTCAGCGCCTCCACCCTGAGAC TCAACCAGAGGCTCCTCCCAGCCCCCAGCACACTAATAAGACAAAGGCCCACTGCTGACT AATTACAGCCACCAATATTTGCTCGGCTAGTATTTATTGGGTCTATATGTTCTGTCCCTC GCATGAGGGATGAGTCATTACCCCATTTCACAGACGAGAAAGTGGGCTCAGAGAAGTGAA ATAACGTATCCAAGGTCATCATAGGGTGTGGTGATTCAGCAGCAACTCTGTCCCCAAAGC CCTTGTTCCTAATCTTTGAGCTGCATTGGATCCCTCTGTGCACCTAGTATTGGTGCACCC AGTTCCTTTTTCAGGAACTTTGCCCTCTCCCTGACCCTGACTCCCACCTGCTCCTCTCCT CTGCTGCCCCTGTCTTATACCCTAAGAAAGGCTGTTGTGGAAAAGGGGGCTCCCTGTGTG CAGAGACAGGGCCTCACCACTTGCCCTCTTCCCCCACAGGAGATCCGGGAGCTGCAGTCC CAGATCTCGGACACATCTGTGGTGCTGTCCATGGACAACAGCCGCTCCCTGGACATGGAC AGCATCATTGCTGAGGTCAAGGCACAGTACGAGGATATTGCCAACCGCAGCCGGGCTGAG GCTGAGAGCATGTACCAGATCAAGTATGAGGAGCTGCAGAGCCTGGCTGGGAAGCACGGG GATGACCTGCGGCGCACAAAGACTGAGATCTCTGAGATGAACCGGAACATCAGCCGGCTC CAGGCTGAGATTGAGGGCCTCAAAGGCCAGGTATGGGCCGGGTTGGGGGTGGGAGGGGTT CCTTGGACACATCCTGGTGAGAGGAGATAATGTAGGAAGAGTGAAGTTTCTGGGAGTCGG GGAAGGAATCCTAGACCAGGGTTCAGGAGTTGGAGGGGCAGCCACAGTTCAGCTTCTCAG TCTGCTTCTGAGAAGCAAAGGGATGCAGGGAAGGTCCCTTGGGCCAGGACAGAGGTGAAA GGGGACTGGGGCAGGTATGTTGGGGCTCGTGATACATGCTCCCAAGCCTGCTTTAATCAG TCATATGCATCAGGGTAAGGTTGAGCTCTGCTGCTTTAAGGAAAGTCTAGAACCCAGGGA TCTAGTCCAGTTAGGGTAGGGGGACCTTACAGTGTCGCAGGTGAGAAGGGTGTGGAGGGG AAGCACCTGGAAACTGCTCATGTCTCCCTGATCTGCTTCCTTAGTCTCGTTTATTTATTT ATTTATTTTTGAGACAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGTGATCT CGGCTCACTGCAAGCTCCGCCTCCTGGGTTCACACTATTCTCCTGACTCAGCCTCCTGAG TAGCTGGGACTACAGGCGCCCGCCACCAGGCTGGCTAATTTTTTTTGTATTTTTACTAGA GACGGGGTTTCACTGTGTTAGCCAGGATGGCCTCGATCTCCTGACCTTGTGATCTGCCCG CCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCCGGCCCTTAGTCT CATTTAATTTGAGCTGGGGGGAGTCAGCCTAGGTGGTGGTGGGGAGGACCCTGAGGGAGG GTGGGAGCACGGGAGAAGAGAAGGCATACCCAACCTGACCTACTTACCTGTCCCCTACCC CACAGAGGGCTTCCCTGGAGGCCGCCATTGCAGATGCCGAGCAGCGTGGAGAGCTGGCCA TTAAGGATGCCAACGCCAAGTTGTCCGAGCTGGAGGCCGCCCTGCAGCGGGCCAAGCAGG ACATGGCGCGGCAGCTGCGTGAGTACCAGGAGCTGATGAACGTCAAGCTGGCCCTGGACA TCGAGATCGCCACCTACAGGAAGCTGCTGGAGGGCGAGGAGAGCCGGTGGGTGTGGGTAC CTCTGACCGGACCTGCTTCCCTATCCCTGGGACCTGGGGTGGGGACGGTGGGAGCCCCCT GAAGCCCCTTGGGACTTGGGGTCCTGTTGTTCTGGGCCAAGAAGGGCTAGGAGTTGGTCC TGACACCCCATTTGTCTGGGTACAGGCTGGAGTCTGGGATGCAGAACATGAGTATTCATA CGAAGACCACCAGCGGCTATGCAGGTGGGTGTCCCAGGGCCCTGGGATGAGGGCGGGAGG CAGGGCCCAGGGAGGCCTCAGCTCCAGGGAGGGGGCTGTGCTCAGTCGCTCACAGTGACC TCAGCCTGAGCACTCATGTTCTTGGGAGAATCCTAGGGTGGGGAGGCACATATTCAGGAC CCCAGTAATAACTTTATTACTTAGTAACTTTACTATTAGAAAGCACCCAAATAAACCATA GCTGTGTGCCAGGCACTGTGCTAAGTATCCTACAGGTTTTATGTGATTTATTTTATTTAT TAATTTAATTTAATTTTTTTGAGACGAAGTCTCGCTCTGTCACCCAAGCTGGAGTGCAGT GGCGTGATCTCAGCTCACTGTAACCTCCACCTCCTGGGTTCAAGAGATTCTCCTGCCTCA GGCCTCCCAAGTAGCTGGGACTACAGGCGCATACCACCATGCCCAGCTAATTTTTGTATT TTTAGTAGAGACGGGGTTTCACTGTGTTGGGCAGGCTGGTCTCGAACTCCTGACCTTGTG ATCAGTGCTGGGATTACAGGCATGAGACACTGGGCCTGGCTGTAATTTATTTTTTATATG ACACCTGTAAACGTCTTCAGTTGAGGAAGCTGAGGTGCAGCTAAATGTCCAAGGTCACAC AGCTATATATATGGCAGCTGTTTTCCACCCTGCTCCTGGTTTTCCCTGACAGTTCTGGAG TAGTGAACCATGCAATCACTGATCAGGCAGAGCTGGGTTAACCTCCCATCCCTGGGGCTA TGTTGGGAATGAGCAGGGAGAAGGGGCATGGAGCCTGCCATGGGGTGGGCTTCTGTACTC ATGTGGCTACCTCTGTCCCTCACCAGGTGGTCTGAGCTCGGCCTATGGGGGCCTCACAAG CCCCGGCCTCAGCTACAGCCTGGGCTCCAGCTTTGGCTCTGGCGCGGGCTCCAGCTCCTT CAGCCGCACCAGCTCCTCCAGGGCCGTGGTTGTGAAGAAGATCGAGACACGTGATGGGAA GCTGGTGTCTGAGTCCTCTGACGTCCTGCCCAAGTGAACAGCTGCGGCAGCCCCTCCCAG CCTACCCCTCCTGCGCTGCCCCAGAGCCTGGGAAGGAGGCCGCTATGCAGGGTAGCACTG GGAACAGGAGACCCACCTGAGGCTCAGCCCTAGCCCTCAGCCCACCTGGGGAGTTTACTA CCTGGGGACCCCCCTTGCCCATGCCTCCAGCTACAAAACAATTCAATTGCTTTTTTTTTT TGGTCCAAAATAAAACCTCAGCTAGCTCTGCCAATGTC OMIM ID 148060