| Entrez gene ID | | 387082 |
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| Official gene symbol | | SUMO4 |
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| Full name | | SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae) |
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| Aliases | | ,IDDM5,SMT3H4,SUMO-4,dJ281H8.4, |
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| Gene summary | | This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq] |
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| Location | | Chromosome: 6 Locus: 6q25 |
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| Gene position | | 149721495 - 149722182 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 688 bp |
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| Gene sequence |
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| OMIM ID | | 608829 |
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