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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TMEM189-UBE2V1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID387522
Official gene symbolTMEM189-UBE2V1
Full nameTMEM189-UBE2V1 readthrough
Aliases,CROC1B,KUA-UEV,UBE2V1,
Gene summaryThe TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q13.2
Gene position48770335 - 48697661  Map Viewer
Gene orientationminus
Gene size72675 bp
Gene sequence