Entrez gene ID | | 387522 |
Official gene symbol | | TMEM189-UBE2V1 |
Full name | | TMEM189-UBE2V1 readthrough |
Aliases | | ,CROC1B,KUA-UEV,UBE2V1, |
Gene summary | | The TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q13.2 |
Gene position | | 48770335 - 48697661 Map Viewer |
Gene orientation | | minus |
Gene size | | 72675 bp |
Gene sequence |
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