| Entrez gene ID | | 3892 |
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| Official gene symbol | | KRT86 |
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| Full name | | keratin 86 |
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| Aliases | | ,FLJ25176,HB6,Hb1,KRTHB1,KRTHB6,MNX,hHb6, |
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| Gene summary | | The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq] |
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| Location | | Chromosome: 12 Locus: 12q13 |
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| Gene position | | 52695649 - 52702947 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 7299 bp |
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| Gene sequence |
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| OMIM ID | | 601928 |
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