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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AFF3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3899
Official gene symbolAFF3
Full nameAF4/FMR2 family, member 3
Aliases,LAF4,MLLT2-like,
Gene summaryThis gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q11.2-q12
Gene position100759037 - 100163715  Map Viewer
Gene orientationminus
Gene size595323 bp
Gene sequence
OMIM ID601464