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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LAMA3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3909
Official gene symbolLAMA3
Full namelaminin, alpha 3
Aliases,BM600,E170,LAMNA,LOCS,lama3a,
Gene summaryLaminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]
LocationChromosome: 18   Locus: 18q11.2
Gene position21269562 - 21535030  Map Viewer
Gene orientationplus
Gene size265469 bp
Gene sequence
OMIM ID600805