| Entrez gene ID | | 3936 |
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| Official gene symbol | | LCP1 |
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| Full name | | lymphocyte cytosolic protein 1 (L-plastin) |
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| Aliases | | ,CP64,DKFZp781A23186,FLJ25423,FLJ26114,FLJ39956,L-PLASTIN,LC64P,LPL,PLS2, |
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| Gene summary | | Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq] |
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| Location | | Chromosome: 13 Locus: 13q14.3 |
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| Gene position | | 46756459 - 46700058 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 56402 bp |
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| Gene sequence |
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| OMIM ID | | 153430 |
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