Entrez gene ID | | 3958 |
Official gene symbol | | LGALS3 |
Full name | | lectin, galactoside-binding, soluble, 3 |
Aliases | | ,CBP35,GAL3,GALBP,GALIG,L31,LGALS2,MAC2, |
Gene summary | | This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants. |
Location | | Chromosome: 14 Locus: 14q21-q22 |
Gene position | | 55595935 - 55612148 Map Viewer |
Gene orientation | | plus |
Gene size | | 16214 bp |
Gene sequence |
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OMIM ID | | 153619 |
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