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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LGALS3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3958
Official gene symbolLGALS3
Full namelectin, galactoside-binding, soluble, 3
Aliases,CBP35,GAL3,GALBP,GALIG,L31,LGALS2,MAC2,
Gene summaryThis gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
LocationChromosome: 14   Locus: 14q21-q22
Gene position55595935 - 55612148  Map Viewer
Gene orientationplus
Gene size16214 bp
Gene sequence
OMIM ID153619