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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARHGDIB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID397
Official gene symbolARHGDIB
Full nameRho GDP dissociation inhibitor (GDI) beta
Aliases,D4,GDIA2,GDID4,LYGDI,Ly-GDI,RAP1GN1,RhoGDI2,
Gene summaryMembers of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM]
LocationChromosome: 12   Locus: 12p12.3
Gene position15114562 - 15094950  Map Viewer
Gene orientationminus
Gene size19613 bp
Gene sequence
OMIM ID602843