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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LIF (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3976 Official gene symbol LIF Full name leukemia inhibitory factor (cholinergic differentiation factor) Aliases ,CDF,DIA,HILDA, Gene summary The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. [provided by RefSeq] Location Chromosome: 22   Locus: 22q12.2 Gene position 30642796 - 30636442  Map Viewer Gene orientation minus Gene size 6355 bp Gene sequence >LIF:complement(10027011..10033365):Length=6355 TACAACACAGGCTCCAGTATATAAATCAGGCAAATTCCCCATTTGAGCATGAACCTCTGA AAACTGCCGGCATCTGAGGTTTCCTCCAAGGCCCTCTGAAGTGCAGCCCATAATGAAGGT CTTGGCGGCAGGTAAATACACCCGCCCCGCGCCGGCTTCGCGTCCCCGCTGCGGGGCGCG GCGGCAACTTGGGGCGCTTGGCAGCGCGAGCCGGACGCCCACCCGCCGCAGACACACGAA CACTTGGGGCGCCCGCGCAGCCACCGGAGGCGCTGGGTGGCGGCCCGGAGCGAGCGCGGG CACATGGTCCCAAGCACCGCACGCCCCGCGGCAGGTTGGCGGCGAGGGAGGGGGCGCCGA GCCTTCCTCCTCCTCCTCTTCTTCCCCCTCTCCTTCTCCTCCTCCTCCTCCTCGCTCCGG ACACTCGCTGGCTGCTCTTCCCTCTGCGCTTTCTCCCAGATTCACTCTCCCTCTCTCTTT TTCTTTTCTTTCTTTCTTTCCGCTTTCTCCTTTCCAACCGCGGTCCCGGGCTGCTCCCAG GGAGGGGCGCGGGCGGCGAGCAGCTTGCAAACTCCGGCCTGGGACGGGAGCAGGTGCCGC CTCCATCTGCTGGTGTCTGGAAGCGTGTGGTCTGCGCTAGGTGAGATATAGGGGTGTGGC CCCCCTCCCGCAGCCACCCCGGGGCCTCAGCACTGCCTTGGGATGCTGGGACGAACAGGG GACCCAGGAGAAGTGAACTTGAGGAGGCCCCTGTCCCCGCTGTTCCAGCATGGGGGATCC GGGGGAGGTCTCCAGCCTCACTCGCCCGCTGACCCCGGCCCCCACCATCTTCAGGTGCCC TTCTGCAGAGCCCTGGAAAAGCGTCTAAGGGGGCCTGGGGGGAGTCGGGAGAACAGGCCC CCCTGGGGGAGGGGCAAACCAGGACATGTCGGGACAGCTCCCAGCTCTCCTGTCACCTTT CACTTTCCTTCCTCCCCGCCCACCCGACTGCCTATGACCTTTTGCCTTTTCTCTCTCCTG GTGCACCATTTCCTCTCCCTCCCTGAGCCGGTGTGTGTGTGTTAGGAGGGAGGGGAACCC CTGGGACAAGGGACAGCGGATGAGTCGGGAGAAGGCATGGAGTCAGGGGCTGTCCGGAGC TGGGGGAACAGAGAGTTTTGAATGATGATTTGGGGATGGAGAGTGGGGACAGCCAGGCAG AAATGGGGTGAGCTTGAGTGAGATAGGGGACACTAGGGAAGGAAGAGATAGAGGATGATG GGGGCGGGGGCAGAATTGGGGGCAATTGGCCCAGGGAGCCAGAATCAAGTGGCAGGTTTG GGAGGGAGATGAGGGTCAACCGAGGACTCCTCCCCACTCCCCCATGCCCCGTGGCCCCCA TGGGTGCCTGGCTTCGGAGATTTGGGCTGCAATGGGCCAGTGAGTGGGAAGCGCTGCTGA GGAACCTGGGCCACCACGGGAGGTGGGAAGAGAGGGGTCTCCTTTCTCCTGGTGCCTGCT GGGCCTGGGGCCTGGTGCCTTCCAGCCAGAGGGCCAGGGGGCCTTAGGACCTTTGCCTTC CTGAGGGAAAGGGTGGGATGGCTGGGAGTCTCTCCTGGACCCTGCACCCTTTGGGTGGAA ATGGCTTGTGTCTTGCCCTCATCTTTACGTCATCCCAGAAGAGAGCAGGGAGAACTAAGG TAGAGAAAGGGAGACAGAGAAACACACGCAGTGACAGAGTGAAGACTAGGCCCCAGGAAG ACAGCTGCAGGTGGTGAGGGGGAACCAGGAGTCCTCTCCCATGCGGCCATTGTTGGACCC CCATCCGGTGTGCCATGACCCCAGGCCACCCTTTCCTGCCTTTCTACTCATGGCTTCTTC CTGACTGTCCCCAGGAGTTGTGCCCCTGCTGTTGGTTCTGCACTGGAAACATGGGGCGGG GAGCCCCCTCCCCATCACCCCTGTCAACGCCACCTGTGCCATACGCCACCCATGTCACAA CAACCTCATGAACCAGATCAGGAGCCAACTGGCACAGCTCAATGGCAGTGCCAATGCCCT CTTTATTCTCTATGTAAGTTACCCCTGGGATACTGACAGGAGATGGCAGGGAGGGGGCTT GTAAATATCATTAGGGGCTGTCCTGATCTGGGTTGAGGGGACCTTTTGGGGCTGGAAGGA GAGAATGGGGAGAGGGCTTGATTAAACCACCCCCAGACTCCCGCCACTTCCTGCCCAAGC TTCCCCAGGGAAGCTTCCCCAGGGTGCCCAGTTAGCAAGGGGAGAACTGAGTGCAAAGGT GGGGACCTGGCACTTCTTATCTTGTGATTGTCCTGCTGCAGGGAGCGAGGGATGGAGGGG AAATGGGCGTGAGGCACCAGGGAGATGCGGTTGAGAGGCAGTGGGCTGTGGGTGCTGGGC ATGGAGGGGCGTCCCGGAACATTGTGAGTGCAGGGATGGAAGTACTTGTGTGTGGTGCCC CAGCTAGGGCTAGACACCGAGTTTTCCCTTCTGTCCCCTTAGGGTGGTGATGATGATGAT GATGATAATGATGACTGCGTGCATGGCTCAGTCTTTGATCTTTAGCAAGGGCACTCACAT TACAATTAGTTTTGGCTCTCATGACAATTCCAGATGCTTACAGGGCAAGGAGTTGGGTCC TCATGCGCTAGATGGGGAAACAGACGCAAGAGCTTGCCCAAAGGGTTGGCGGCAGGGCTG GGACACTGACCCCTGACTCCCACGTCACCTCCCTTCTGCCCCTCAGTACACAGCCCAGGG GGAGCCGTTCCCCAACAACCTGGACAAGCTATGTGGCCCCAACGTGACGGACTTCCCGCC CTTCCACGCCAACGGCACGGAGAAGGCCAAGCTGGTGGAGCTGTACCGCATAGTCGTGTA CCTTGGCACCTCCCTGGGCAACATCACCCGGGACCAGAAGATCCTCAACCCCAGTGCCCT CAGCCTCCACAGCAAGCTCAACGCCACCGCCGACATCCTGCGAGGCCTCCTTAGCAACGT GCTGTGCCGCCTGTGCAGCAAGTACCACGTGGGCCATGTGGACGTGACCTACGGCCCTGA CACCTCGGGTAAGGATGTCTTCCAGAAGAAGAAGCTGGGCTGTCAACTCCTGGGGAAGTA TAAGCAGATCATCGCCGTGTTGGCCCAGGCCTTCTAGCAGGAGGTCTTGAAGTGTGCTGT GAACCGAGGGATCTCAGGAGTTGGGTCCAGATGTGGGGGCCTGTCCAAGGGTGGCTGGGG CCCAGGGCATCGCTAAACCCAAATGGGGGCTGCTGGCAGACCCCGAGGGTGCCTGGCCAG TCCACTCCACTCTGGGCTGGGCTGTGATGAAGCTGAGCAGAGTGGAAACTTCCATAGGGA GGGAGCTAGAAGAAGGTGCCCCTTCCTCTGGGAGATTGTGGACTGGGGAGCGTGGGCTGG ACTTCTGCCTCTACTTGTCCCTTTGGCCCCTTGCTCACTTTGTGCAGTGAACAAACTACA CAAGTCATCTACAAGAGCCCTGACCACAGGGTGAGACAGCAGGGCCCAGGGGAGTGGACC AGCCCCCAGCAAATTATCACCATCTGTGCCTTTGCTGCCCCTTAGGTTGGGACTTAGGTG GGCCAGAGGGGCTAGGATCCCAAAGGACTCCTTGTCCCCTAGAAGTTTGATGAGTGGAAG ATAGAGAGGGGCCTCTGGGATGGAAGGCTGTCTTCTTTTGAGGATGATCAGAGAACTTGG GCATAGGAACAATCTGGCAGAAGTTTCCAGAAGGAGGTCACTTGGCATTCAGGCTCTTGG GGAGGCAGAGAAGCCACCTTCAGGCCTGGGAAGGAAGACACTGGGAGGAGGAGAGGCCTG GAAAGCTTTGGTAGGTTCTTCGTTCTCTTCCCCGTGATCTTCCCTGCAGCCTGGGATGGC CAGGGTCTGATGGCTGGACCTGCAGCAGGGGTTTGTGGAGGTGGGTAGGGCAGGGGCAGG TTGCTAAGTCAGGTGCAGAGGTTCTGAGGGACCCAGGCTCTTCCTCTGGGTAAAGGTCTG TAAGAAGGGGCTGGGGTAGCTCAGAGTAGCAGCTCACATCTGAGGCCCTGGGAGGCCTTG TGAGGTCACACAGAGGTACTTGAGGGGGACTGGAGGCCGTCTCTGGTCCCCAGGGCAAGG GAACAGCAGAACTTAGGGTCAGGGTCTCAGGGAACCCTGAGCTCCAAGCGTGCTGTGCGT CTGACCTGGCATGATTTCTATTTATTATGATATCCTATTTATATTAACTTATTGGTGCTT TCAGTGGCCAAGTTAATTCCCCTTTCCCTGGTCCCTACTCAACAAAATATGATGATGGCT CCCGACACAAGCGCCAGGGCCAGGGCTTAGCAGGGCCTGGTCTGGAAGTCGACAATGTTA CAAGTGGAATAAGCCTTACGGGTGAAGCTCAGAGAAGGGTCGGATCTGAGAGAATGGGGA GGCCTGAGTGGGAGTGGGGGGCCTTGCTCCACCCCCCCCCATCCCCTACTGTGACTTGCT TTAGGGTGTCAGGGTCCAGGCTGCAGGGGCTGGGCCAATTTGTGGAGAGGCCGGGTGCCT TTCTGTCTTGATTCCAGGGGGCTGGTTCACACTGTTCTTGGGCGCCCCAGCATTGTGTTG TGAGGCGCACTGTTCCTGGCAGATATTGTGCCCCCTGGAGCAGTGGGCAAGACAGTCCTT GTGGCCCACCCTGTCCTTGTTTCTGTGTCCCCATGCTGCCTCTGAAATAGCGCCCTGGAA CAACCCTGCCCCTGCACCCAGCATGCTCCGACACAGCAGGGAAGCTCCTCCTGTGGCCCG GACACCCATAGACGGTGCGGGGGGCCTGGCTGGGCCAGACCCCAGGAAGGTGGGGTAGAC TGGGGGGATCAGCTGCCCATTGCTCCCAAGAGGAGGAGAGGGAGGCTGCAGATGCCTGGG ACTCAGACCAGGAAGCTGTGGGCCCTCCTGCTCCACCCCCATCCCACTCCCACCCATGTC TGGGCTCCCAGGCAGGGAACCCGATCTCTTCCTTTGTGCTGGGGCCAGGCGAGTGGAGAA ACGCCCTCCAGTCTGAGAGCAGGGGAGGGAAGGAGGCAGCAGAGTTGGGGCAGCTGCTCA GAGCAGTGTTCTGGCTTCTTCTCAAACCCTGAGCGGGCTGCCGGCCTCCAAGTTCCTCCG ACAAGATGATGGTACTAATTATGGTACTTTTCACTCACTTTGCACCTTTCCCTGTCGCTC TCTAAGCACTTTACCTGGATGGCGCGTGGGCAGTGTGCAGGCAGGTCCTGAGGCCTGGGG TTGGGGTGGAGGGTGCGGCCCGGAGTTGTCCATCTGTCCATCCCAACAGCAAGACGAGGA TGTGGCTGTTGAGATGTGGGCCACACTCACCCTTGTCCAGGATGCAGGGACTGCCTTCTC CTTCCTGCTTCATCCGGCTTAGCTTGGGGCTGGCTGCATTCCCCCAGGATGGGCTTCGAG AAAGACAAACTTGTCTGGAAACCAGAGTTGCTGATTCCACCCGGGGGGCCCGGCTGACTC GCCCATCACCTCATCTCCCTGTGGACTTGGGAGCTCTGTGCCAGGCCCACCTTGCGGCCC TGGCTCTGAGTCGCTCTCCCACCCAGCCTGGACTTGGCCCCATGGGACCCATCCTCAGTG CTCCCTCCAGATCCCGTCCGGCAGCTTGGCGTCCACCCTGCACAGCATCACTGAATCACA GAGCCTTTGCGTGAAACAGCTCTGCCAGGCCGGGAGCTGGGTTTCTCTTCCCTTTTTATC TGCTGGTGTGGACCACACCTGGGCCTGGCCGGAGGAAGAGAGAGTTTACCAAGAGAGATG TCTCCGGGCCCTTATTTATTATTTAAACATTTTTTTAAAAAGCACTGCTAGTTTACTTGT CTCTCCTCCCCATCGTCCCCATCGTCCTCCTTGTCCCTGACTTGGGGCACTTCCACCCTG ACCCAGCCAGTCCAGCTCTGCCTTGCCGGCTCTCCAGAGTAGACATAGTGTGTGGGGTTG GAGCTCTGGCACCCGGGGAGGTAGCATTTCCCTGCAGATGGTACAGATGTTCCTGCCTTA GAGTCATCTCTAGTTCCCCACCTCAATCCCGGCATCCAGCCTTCAGTCCCGCCCACGTGC TAGCTCCGTGGGCCCACCGTGCGGCCTTAGAGGTTTCCCTCCTTCCTTTCCACTGAAAAG CACATGGCCTTGGGTGACAAATTCCTCTTTGATGAATGTACCCTGTGGGGATGTTTCATA CTGACAGATTATTTTTATTTATTCAATGTCATATTTAAAATATTTATTTTTTATACCAAA TGAATACTTTTTTTTTTAAGAAAAAAAAGAGAAATGAATAAAGAATCTACTCTTG OMIM ID 159540