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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LMX1A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4009
Official gene symbolLMX1A
Full nameLIM homeobox transcription factor 1, alpha
Aliases,LMX1,LMX1.1,MGC87616,
Gene summaryInsulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]
LocationChromosome: 1   Locus: 1q22-q23
Gene position165325952 - 165171104  Map Viewer
Gene orientationminus
Gene size154849 bp
Gene sequence
OMIM ID600298