Entrez gene ID | | 400961 |
Official gene symbol | | PAIP2B |
Full name | | poly(A) binding protein interacting protein 2B |
Aliases | | ,KIAA1155, |
Gene summary | | Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM] |
Location | | Chromosome: 2 Locus: 2p13.3 |
Gene position | | 71454233 - 71409868 Map Viewer |
Gene orientation | | minus |
Gene size | | 44366 bp |
Gene sequence |
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OMIM ID | | 611018 |
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