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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LPA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4018
Official gene symbolLPA
Full namelipoprotein, Lp(a)
Aliases,AK38,APOA,LP,
Gene summaryThe protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q26
Gene position161087407 - 160952515  Map Viewer
Gene orientationminus
Gene size134893 bp
Gene sequence
OMIM ID152200