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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LTC4S (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4056 Official gene symbol LTC4S Full name leukotriene C4 synthase Aliases ,MGC33147, Gene summary The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq] Location Chromosome: 5   Locus: 5q35 Gene position 179220986 - 179223513  Map Viewer Gene orientation plus Gene size 2528 bp Gene sequence >LTC4S:24032259..24034786:Length=2528 TCTTCCTCTCCTGGGCCGTCCTCTGAGCAGCAGACGGGGCTAAGCGTTCCCCAGCTCGCC TTCACACACAGCCCGTGCCACCACACCGACGGTACCATGAAGGACGAGGTAGCTCTACTG GCTGCTGTCACCCTCCTGGGAGTCCTGCTGCAAGGTGGGCTGGTTCCTATCTAGGAAGAG GGTGGGCCTTAGATCCCTACAGCTTGCCCTCTGCCCCCTAGGCCCAGGTGGAGGGCAGAG GTGGGGACTCCAGCCCAGGCCCAAGCTGGAAGAGGGTGGGGACTTTCAGGGAACTGGGGG GCACCTGGCTGTGAGAGCTGTAGGACTTGGGGGTGGCAAGGGTGCCAGGACAAATGGTAG GATAGCCATGGGCTTGGGGAAGCTGATCTCTGCTCTTTCCAGCTGTCCCCTCTCTGGGCG TCCCAGCAAGCGGCCCCCATTCCCTGGCTCTGCTTCAAAGGCACCTCCATACTGGGACCA CGTGGAGCAGGGTAGAGGTGGGACTCCTTCCTCCAGCCCCCTAAAAAGAGCCTGCTTAAT GCCTTTCTCAGACTGGCCCTAAAGGACACATTCCTTGGCCAGATATCCTTGCCACCTAAG AGACACCACTACTCCACAGTGTGTGGGCTAGGATAAGGCACAGCCTGGGGAGGGGGCTCT GAAGGGGCTGAACAGACAGGCCAGCCTGACCTCCAGCTGCTCCTGCACTGAGCTGGATGG CCACCCTGTGACACCCATCTGCAGAGGGCCCAGAACCAAAGGTGCCAGGGCTGCAGGACT CAGGGGGAGATGGTCCGACGGGAGGTCTGGGGAGGGAGCGCACAGCCAGCACTGGTCTGT GTGTGGTCTGGCCTGGCCTCACCTGACCAAGAGAAGGGCTCCTGCCCACAGAGAAACTTT AGGGCCAGCCCACCCTCTGCAACTACCCCAGCCCTGGGGTCCTGGGGTTAGGCTAGGAGA GTCCCAGCTGCAACCTCCTGGGAGCAGGAGAGAAGGTGTCTGTCAGATTTAGGCCTGGGA CCGGAATGCAGGAACAGAGAAACTGAGGTTTGGAGGCACAGGGACGCAGGCTTTAGTGAT CCCGGCCTGAGGCAGGGTCAGAGGGCCCTGCTGGTGGGCGCTGGTAGGTGGGTGACCAGG GACTGTTAGCTACAGGGAGTGTGCTTCCTTGCACCTGGGAGGATGCAGCCAGCTCTGCCC TCAGACTCCCGAGGCACTTCCTGGCCAGGGACCTGAAAGCTGCATTTGCCTGTGTTTTGA GAGTGAAATGATTCAGAAACAAGGACTCAAGTGGTCTCTCTCGCGGAGCAGGTGTCCCTG TGCCTGAATCACTCACCCTCCCCCATACACTCACAGGTTGGGACAGGGCCTCTCTGCGCC CCAGGCTTCAGCCCTGCCCTCCTCGCTGAATGTCAGGGACACAGGGCAGGCCAGGGATGG GTGAGACGAGAGGTCTCCTCGGGCGGGGAGGGGGCGGGGTTCCGCCTTAGGGAGGAGAGG ACACGGCCAAGTGAAGGGCCAGATTGCAGGATCCCTCCCACTCCCATCTCTGGGGCTTCG GGTGTCCAGACCTGACTCCCGCTCCCCCTCCTCCCCCAGCCTACTTCTCCCTGCAGGTGA TCTCGGCGCGCAGGGCCTTCCGCGTGTCGCCGCCGCTCACCACCGGCCCACCCGAGTTCG AGCGCGTCTACCGAGCCCAGTGAGGCGCGGCGGGAGGGCGCGGGGCGGGGAGCGAGCCCC AGGCGGGTCCGGGTCGCAGGACCATCCCGGCCGGCGCGCTCATCCCACCCGCCCACCGCA GGGTGAACTGCAGCGAGTACTTCCCGCTGTTCCTCGCCACGCTCTGGGTCGCCGGCATCT TCTTTCATGAAGGTCGGGGTGTGGGGCAGGGGCGCACGCGCTGGACCCCCGGGACCCGCG CAGGGCGCTCACCAGGCCCGTGCGTACCTCTCGCAGGGGCGGCGGCCCTGTGCGGCCTGG TCTACCTGTTCGCGCGCCTCCGCTACTTCCAGGGCTACGCGCGCTCCGCGCAGCTCAGGT GAGGGCCGGGCGGGGAGCGGGGCGGGGCCGGGGAAAGATCGCGGGCGGGCGGGGCTCCTG GGGAGCGGGACCGAAGCTGGGGGCGGGCGACGGGCCGGAGCCCAGCGCCTTTGGGGATTC GGTGGGCGAGCCCTGGCGGCGGCCAGAGGAAGTCCCCGTGGGGCCAGGGTTGCGGCGGGG AAGAAGCGGGCCTCCTCGCGCCACCTCCCCGCTGACCGCCGCCCGCAGGCTGGCACCGCT GTACGCGAGCGCGCGCGCCCTCTGGCTGCTGGTGGCGCTGGCTGCGCTCGGCCTGCTCGC CCACTTCCTCCCGGCCGCGCTGCGCGCCGCGCTCCTCGGACGGCTCCGGACGCTGCTGCC GTGGGCCTGAGACCAAGGCCCCCGGGCCGACGGAGCCGGGAAAGAAGAGCCGGAGCCTCC AGCTGCCCCGGGGAGGGGCGCTCGCTTCCGCATCCTAGTCTCTATCATTAAAGTTCTAGT GACCGAGA OMIM ID 246530