Entrez gene ID | | 4057 |
Official gene symbol | | LTF |
Full name | | lactotransferrin |
Aliases | | ,GIG12,HLF2,LF, |
Gene summary | | This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p21.31 |
Gene position | | 46506395 - 46477496 Map Viewer |
Gene orientation | | minus |
Gene size | | 28900 bp |
Gene sequence |
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OMIM ID | | 150210 |
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