Entrez gene ID | | 4072 |
Official gene symbol | | EPCAM |
Full name | | epithelial cell adhesion molecule |
Aliases | | ,DIAR5,EGP-2,EGP314,EGP40,ESA,GA733-2,HNPCC8,KS1/4,KSA,M4S1,MIC18,MK-1,TACSTD1,TROP1, |
Gene summary | | This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p21 |
Gene position | | 47596287 - 47614167 Map Viewer |
Gene orientation | | plus |
Gene size | | 17881 bp |
Gene sequence |
| |
OMIM ID | | 185535 |
|