Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MIR17HG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID407975
Official gene symbolMIR17HG
Full nameMIR17 host gene (non-protein coding)
Aliases,C13orf25,FLJ14178,MGC126270,MIHG1,MIRH1,MIRHG1,NCRNA00048,miR-17-92,
Gene summaryMicroRNAs (miRNAs) are small regulatory RNAs that control gene expression by binding to complementary sites within target mRNAs and mediating their degradation or translational repression. MIR17HG is the host gene for the MIR17-92 cluster, which is also called ONCOMIR1, and encodes a polycistronic primary transcript that yields at least 6 mature miRNAs: MIR17 (MIM 609416), MIR18 (MIR18A; MIM 609417), MIR19A (MIR19A1; MIM 609418), MIR19B (MIR19B1; MIM 609419), MIR20 (MIR20A; MIM 609420), and MIR92 (MIR92A1; MIM 609422). MIR17-92 functions in cell survival, proliferation, differentiation, and angiogenesis and is the primary target of genomic amplification of chromosome 13q31 that occurs in several lymphomas and solid tumors (summary by Olive et al., 2009 [PubMed 20008935]).[supplied by OMIM]
LocationChromosome: 13   Locus: 13q31.3
Gene position92000074 - 92006829  Map Viewer
Gene orientationplus
Gene size6756 bp
Gene sequence
OMIM ID609415