Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAP4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4134
Official gene symbolMAP4
Full namemicrotubule-associated protein 4
Aliases,DKFZp779A1753,MGC8617,
Gene summaryThe protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p21
Gene position48130769 - 47892180  Map Viewer
Gene orientationminus
Gene size238590 bp
Gene sequence
OMIM ID157132