Entrez gene ID | | 4225 |
Official gene symbol | | MEP1B |
Full name | | meprin A, beta |
Aliases | | ,-, |
Gene summary | | Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha (MEP1A; MIM 600388) are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins. See MIM 600388 for further information on meprins.[supplied by OMIM] |
Location | | Chromosome: 18 Locus: 18q12.2-q12.3 |
Gene position | | 29769987 - 29800367 Map Viewer |
Gene orientation | | plus |
Gene size | | 30381 bp |
Gene sequence |
| |
|