Entrez gene ID | | 4233 |
Official gene symbol | | MET |
Full name | | met proto-oncogene (hepatocyte growth factor receptor) |
Aliases | | ,AUTS9,HGFR,RCCP2,c-Met, |
Gene summary | | The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7q31 |
Gene position | | 116312459 - 116438440 Map Viewer |
Gene orientation | | plus |
Gene size | | 125982 bp |
Gene sequence |
| |
OMIM ID | | 164860 |
|