Entrez gene ID | | 4277 |
Official gene symbol | | MICB |
Full name | | MHC class I polypeptide-related sequence B |
Aliases | | ,PERB11.2, |
Gene summary | | This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p21.3 |
Gene position | | 31465855 - 31478901 Map Viewer |
Gene orientation | | plus |
Gene size | | 13047 bp |
Gene sequence |
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OMIM ID | | 602436 |
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