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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAP3K11 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4296
Official gene symbolMAP3K11
Full namemitogen-activated protein kinase kinase kinase 11
Aliases,MEKK11,MGC17114,MLK-3,MLK3,PTK1,SPRK,
Gene summaryThe protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13.1-q13.3
Gene position65381720 - 65365226  Map Viewer
Gene orientationminus
Gene size16495 bp
Gene sequence
OMIM ID600050