Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP7 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4316 Official gene symbol MMP7 Full name matrix metallopeptidase 7 (matrilysin, uterine) Aliases ,MMP-7,MPSL1,PUMP-1, Gene summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq] Location Chromosome: 11   Locus: 11q21-q22 Gene position 102401478 - 102391239  Map Viewer Gene orientation minus Gene size 10240 bp Gene sequence >MMP7:complement(5953655..5963894):Length=10240 ACCAAATCAACCATAGGTCCAAGAACAATTGTCTCTGGACGGCAGCTATGCGACTCACCG TGCTGTGTGCTGTGTGCCTGCTGCCTGGCAGCCTGGCCCTGCCGCTGCCTCAGGAGGCGG GAGGCATGAGTGAGCTACAGTGGGAACAGGCTCAGGTATGTCACAGCCCACTTACTTAGG GTTCCATTCTTTTGCCATCTGCATTAAGAAATGTGTTTTTCAATTATTTCCCTTCCCATG TTAGCATTGCAGTGGAATTTTCTTTGGGGTGGTTCTTCGGATTATAAAAGCAATATATGT TTTCATCAAGTAGCCATTAAAAGCAGGTTTCAGAATCTGCTCAAATCGGGCTTGAGTTCC AACCCTCCACTCACTATGTAGATAGACTCAGGAAGGTCATCAAACTTCTCTAAGCTTCAG GTTTCCAATTTGGAAGTTGGAGATAAGAATGGTATCAACCAAATGAGGGTGTTGTGAAGC ATTCAACACAATACCTGAAACATTGTTTAAATTAAGTTCTTATTTTTATTTATTATAACT TGAGATTCTTTTTCTATAGTATACAGAATATTGCCTCTTAAGATACAACCTGTAAATATA CTGTTTGTGTATTTACAATACTGTTTGTAATGGAGATATCTGAAGTCAGAAAACATGGGT AGAAATTACAACTCTCCAACAAGTCAATGACAATAGACAAGGCATTAACATCTGACTTTG TTTTCTCATGTGTCCAGTAGAAAAAATAATATTATGTGTTTTATACCTCATGGGGTATTC TAGTAAGTAAATGAGGTGATAACAAAACCAACTAGCATGTATGTAACAATTGTAGATTAT AAAGTACTTATATAGACATTGTGTCATTTAATCCTTAGTTCTATAAAAAGAGGAAACCAA AGTTAAACTGATTAGTGTACTTATTAGTGGTAGAGATAGAAATCAAGGACAAGTGCTTCT GGTTCAAAAATCATGTTCCTTGCAATATGCTTCTTAATAAGCAGTCTAATAAATATAAGC AGTCTACTAATTATTATTTGGTTAACTAATGGGATGATTACTTATAACTATTATTTGTAA ATTTAGGCCTTAAGCATAAGAAAAGTCAATTTTTAATTCACATTAACTTAGACTTTTAAA AAGTTCCAGTTATAATAAGTTAGATTGAACCACATAAAGTTACTAGTATTTAACTTTTAA AATCTCCAAAACAGTAGTTTTATATGGTTCCACCTAATGAATTCTCCAGAAAGAGTACTC TGCGTTTAGTTTCTTTACTTAGAGTGAAGGTTGGCAGAAACTTAGTCTTCACTTGGAGGG ATGTTAGCTAGGTTTAACAAAAAAACAGGAAAAGTCATCTCAACAAAGCAGAGAGATTTC TTCCAGAGGGTGTCTTGGTAAAGTCTGTAGCTCTAGAAGGGATTAAATGGGTTATTTGTT TTTAAATAAAGGATCAGTTATCAATTGTCATGGATGAACAATAAGTATTTGTTGTATTTA ATGAGACAATTGTTGGTAACAGGAAAAAAAGACACAATATTAATAAGATTTCTTACATAA ATTGCATATTCCTGGGCGGTCCTAAGACAGGTAACCATTACCATCTACTCCAAATAAACT GCAAATTAGTGAGCCAATGTTTAAATCATTTTAACAACAATATTATCAGGCATCATATAA CCCTACACATGTTTCTAATGTATAGAAGTCAGAACACTTGAGTTCAAATACTGGTTCCTT CAGTTACTCACAAGGTGATCTTGTGCAATTTATTTCACTTCTCTGAGCTGTGTTTCTTCA TGTATAAAATAGGGATAACAATGCCATACTTGTTTCATAGAGTGGTTATGAGGTTTACAT AAAATAAATATGTAAGTGCCTGGCTCTAGTAAGTGCTTAAAAATGTTCCTGTGAGGTTGC TATTGTTGTTAGTTCATTCACTTTTGTTGTTGTTGTATTTGTGCTGCTGGATTCCTATCC TCATATTCAGATACTGAGAAACTTTAGAGAAATTCCCAGGAATCCAACCTTGCATGGAAT AAACCTGGGAGTCCTACTGTATACTGCAATCTCCCAAAGTGGGTTTGACTAGAGATTTAA CAGCAGAAAGAAGGGCTGGGAATGGAATGAGCAGAAAGAGGGAAAAGAGGACCTAGGAGT CAGGAAAGTCAAGTCCAGTTCTGCTACTAATTTAAGGTGTGAACCTGGGCACATAAATCA TTTAGTTGCTATAAGCTTTGGTTCCTTCACCGGATTATTAAATTGAACTATTTAATAATT TCCTAATATCTTTTCCCAGAGCTAAAATTTTAAGACCCTTTAACTTTTAGCTGGAACCGC ATCTCAGCTGGACTTTAGATAGGGCTGGTTGACCTCAGATCTCCCCCACAGGGTCTATGA TAACACAGAGAATGTCCCAGTCGTACCCCTGAGGACAGACTGGTACATGCTTCCTGATTG CTCTTACACACTTCTAGGCTTTATAAAGTGTACAGTGTAATTCTCCCCAAAACATTTAAA TGGATTTTTTAAAAATTGAGGGATTCTTTTCTTTTGCTCACGAAATGGCACGCCAGTGCT TCATTAGCAATATTAAATTTTCTCCTCACTAATGCACACTTATTTTTCTCTGTGACTATG TAATTATTCTGTCTTCAAATCATTATTTGAATTCACAGGAACCAAAGGCAAGAGATATAT AGGCTTCTAAGATAAAAGAATATAATAAACAAGAACTATAGATTAATTACTCTCTTTTCA ATAGGACTATCTCAAGAGATTTTATCTCTATGACTCAGAAACAAAAAATGCCAACAGTTT AGAAGCCAAACTCAAGGAGATGCAAAAATTCTTTGGCCTACCTATAACTGGAATGTTAAA CTCCCGCGTCATAGAAATAATGCAGAAGCCCAGATGTGGAGTGCCAGATGTTGCAGAATA CTCACTATTTCCAAATAGCCCAAAATGGACTTCCAAAGTGGTCACCTACAGGTTAGTTTT GCTCTGGCTCATTTTGGCAAAAACAATAAAGCCTGTTTCCTAGGGGTCAAACATTGTTTT CTTGTTTGCTACTAGGATCGTATCATATACTCGAGACTTACCGCATATTACAGTGGATCG ATTAGTGTCAAAGGCTTTAAACATGTGGGGCAAAGAGATCCCCCTGCATTTCAGGAAAGT TGTATGGGGAACTGCTGACATCATGATTGGCTTTGCGCGAGGAGGTAAGAAAGATTCCTG TAGGCTAATCCTGTGTCCTGTTTTGTTTGTTCATGGTTTATATCAGTGCTCTTTTCTTAT GAAGATTAAAATCCTTTAATGAGATATGATTGGTAGATAGATAGTTAATAGATAGATTTA GCAATATTATTATAATTTTTATAATCTGGTAATATAGAGCCACTTTTTATAGCAGCAGTT GGCAAACTATGATGCATGAGCCAAATCCAGCCCACCTTCTGTTTTTGTAAATAAAGTTTT ACTGGAACACAGTCAGGCTCCTTCATTTCCCTATTACCTATGACTGTTTGGGCTCAGGCT GCAACTGTGACAGAGATCACAAAGCTTAAACACTTGTTATCTGACCCTTTACAGAAAAAG TTTGCCAACCCCTGTTTTGTAACGTGAATTATTATTTATATATACAGTCATGCACTGCTT AACAATGGGAATACACTCTGAGAATGAGAACTTTGGCAATCTTGTCACTGTGCTAACATC ATAGAATACACTTACACAAACCCAGGTGATACAGCCCACTATCCACCTAGGCTACATAGT ATAGCCTATTGCTCCTAGGCTGTAAATCTATACAGCATGTTACTATACTGAATACGGTAG GCAACTGTAACACAGTGGCAAGTATTTGTGTGTCTAAACGTATTTAAACATTGAAAAGGT AATGTATTGAGCTATGACATTATCACAACTACTATATCACTAGGCTATAGGAATTTTTCA GCTCCATTATAATCTTATAGGACCATTGTATATGTGATCTGTTTACTGAAAGATCATTAT GTAGCACATGACTATATGTTTACAATATATCTACCTAACATCGATATTAAATCAACAGAA AGAGTCGCAGCTTCCAAAGGCCTCAAGAGTCCCCTGAGAAGTGGTATATGACCTGTTGCT AATGCCTTTCATGTGGCAAGGAAGTAGGAAATGGAAACTTTCATATTAAAGAACTTAAAA ATATATAACACAGCAGGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTCGGGAGGCCA AGGCAGGTGGATCATCTGCGGTCAGGAGTTCAAGACCAGCCTGGCCAATAGGGTGAAACC CCATCTCTACTAAAACAAAAATTAGCTGAGCATGGTGACGCATGCCTGTAATTCCAGCTG CTTGGGAGGCTGAAGCATGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCAATGAGCCA AGGTCACACCACTGTATTCCAGCCTGGGCAACAGAGCAAGACTATGTCTCAAAAGAAAAA AAAAAAATATATATATATATATTTTTTTTTTTTACGTGGGTTTTTCTATATGTAAAACCC ATTTTTTTAGTATATGTGTTATATATGTGTGTGTGTGTATATATGTATATATAAAACCCA TATACATAAATTGTTCTTAATTGCTAGTGTTTCATGGTGCAAATTTAGAGAAAAATGTTG CCCATTTCAGTCTGTTCTATGTGGAATGGTCCGGCTACTGTAGCTGAAATTTGAACTTCA ACCCACAATATTGACAACACCGAAGAAAATGTTATGGGAAAGCACTAATCATGGCACTAC AAGTTTTTTAAGAGCTAGATAAACTGGACTGGCCTCATATCACCTCGAAGATAACCAGCT CTGCATCACACATTAAAGGACTATAAAAAGCCATTTTAAGAGATCTTGAGCATGGCTCTC TAAGAGACTATTTACTATGCCCACGAAGAATAAGCTAGGTTTTTAAGAAAAAAAAAAAAA AAAACCTATGAAATGGTGCACAAATTACTTGCCAAATGTGGTATTCATATTCATTCTCCC TCCCACCACCCTTTGGCCGAGCAAAGTGGTCAAATTTAACAAAAGCTTAAATGCAACCTT AAGTTAGATATAACTGCATTTTAAGTCCTGTATCCAGTAAGCTTTCAATATATGGTGATT ATCAGTGATGAGCAATGGTTCTGTGAAAGGAAAAGTGTCTGGGCCAAGAAAGCACCCAAA CTACCCTGTGAGTGCAACCGACAGCACATAACAATGTCAGCTACTTGCACTGGGCTGCCT TTTTTTTTTTTTTAATTTATTTTTTGAGATGGAGTTTCACTGTTGTCACCCAGGCTGGAG TGCAGTGGCGCGATCTCAGCTCACTGCAACTTCCGCCTCCTGAGTTCAAGCAATTCTCCA GCCTCAGCCTCCCAAGTAGCTGGGATTACTACTTGGTGGCATGTGCCACCATGTCCAAAT TTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGACAGGTCTCAAACTCCT GACCTCAGGTGATCCGCCCACCTCGGCCTCGCAAAGTGAGCCACCATGCCTGGCCTGGAC TGGGCTGCTTTTTCTAGCCTCAATAATCGTATAAACTGAAAAATAAAATGACTGGAGAAA AAAAAAATCAGTCACTAAGAACAATCACTCCATTTTCTTTCAGCTCATGGGGACTCCTAC CCATTTGATGGGCCAGGAAACACGCTGGCTCATGCCTTTGCGCCTGGGACAGGTCTCGGA GGAGATGCTCACTTCGATGAGGATGAACGCTGGACGGATGGTAGCAGTCTAGGTATAGCA TCTCATGTCTCTTCTACTCCACATCCGTTTTAAAATCCTGGACTTACACTAAGTTAAATA ATTATATTAATTTATAATAAGTATTGAGCCCTTGCTAAGTGCCAAACACTGTACTATATG CCTGAAATGCATTATTTCATGTAATATACTCATAATGCTACACACAGAAGATGGACACTC AGGCTATGGAGTCAAGCACCACTGATCCAATTTGCTGTACGTCTACCAATTACTCTGTGT CATTGGGCAAGTTATTGAATTTCTCTGAGCCTCAGTTTCCTCCTCTGTGGAATGGAAATA TAAATAGTTCCCACATCAAGGAGTCTTTAAATTAAATGAGATAATGCTTATACAGTGCTT GGAATGTATTAATAATTAATTAAATTATAGCTCTTTCTTCATATTTCCAAAAAATACATG CCCCAAATGGAAAAGAAAGAGAAGTAGAAACTATGATATTTGAGAAGTATATGCAATTCT GGAATTATTCACTATTTTCCAGAAAGAACCAACTCCATGATTTAGTATATCATATTTATC ATTTTACATAGTAGGATATTATAGGCACATGAGAGAACTAATGGAGAAGAGCTCTGGCAT AAATAATCCCAATTAGAGACAATTTTTTTAAGGCTACCAACTGGCCCTAAAAGGGAAATT TGTACTTGTGTTTGGCAAAAGGAATTCACCATAGCTTGCTGTCTTGCTGTGAAAATCTAT GTTAAATTGTGATGCTGCCTCCCATTTGCATCTGGCATATTCTTTTCATTCTTCTTTCTT CCCACTTAAGGTAGGTTAAAGGCAGCTTCCTTCAATTCAATGCAACGCCACCAGAGCTCA GGCCACTCCTCAAACGCACGGGCTCACACCTTCCACATACTTGCAAAGCCTTTCAATGAG TATGAGGGAGAACAAAGGATATATGTAATACAAGTTAATGAATCAAAATCAAAAACAAAG CCCAGCATTGCCTAGAGACCCTGCCTTTCAATCTTCGCTTTCTCAAAGCCACCATTCTCT CTTCTGATATCCAAAGTCACTAACATTTATTGAATGGCCGTGACTTCCCAAATATTGAGA AACTCTAGCTATCATGACAAATCTAGAGGGCAGAAATTACTGTCTCTGTTTAACAGATGA GAAACTGAGACTCAGCAACATCAATTAATCTGTCCAGAGTTGTCCAGCTAGTAAGTAGTG GAGCTACATTTCAAACCTAGGTCTTAGTGCTTTTAAAACCTTTGCTTTCCACTGCAGAGT ATTGCTGCCTGAATGAAAGAAGCAAATAAAAAAAATTACACATTTTTAATAAGCAGAAGT AGTGATGAGATTAAAGCACTCCTATTCTGATTAACCTTCTAACCCCTCTCCACTTTTGAA AGCCTAGAAACAAATAAGTAAGCTACCGTGGGCTAAAACTTGGGTATTTTTCTTTAGTTT TTTTAAATTATGATATCATATATATAATATTACATAATGTATGTAGCTATTTTTATCATT ACTGTTTGTCACTTCTTCGGTTGTAGGGATTAACTTCCTGTATGCTGCAACTCATGAACT TGGCCATTCTTTGGGTATGGGACATTCCTCTGATCCTAATGCAGTGATGTATCCAACCTA TGGAAATGGAGATCCCCAAAATTTTAAACTTTCCCAGGATGATATTAAAGGCATTCAGAA ACTATATGGTAATATTTATTATTTCAAATAAGAGGATTTCCCATTTTCTTTTTAGAGTGG GGTAGGAAAAGAAAGGCTGGGAAATGGGTATTTACCTGGAAAACCACACTGGAACTCATA TCAAAAAGCCTATTGAGGGGAGGAATTGGGGACCTTAGATACTTAAAATATAACTAGGCT GTAATATACTATGAAGATGTTGATTGTGAGTTTCAGTAACATAGTATCATGTGGTAAAAT TATGCAAATGATATTGTCCAGATTTTCTTCAAGCTGCCACCCACTGCTCTTCCTCTCTCA GTTTAAATAGTTTAGGAGAGTGTCCCCTGTAGGGGTGGACTGAAGGGACAAAACACCTTT CTTCATAGCTGCCCACTCCTAAGGATTCAATCCTAGATAATTATAAGTGACCCTGCTCTT CCTGTTTGCACGTACATGTAGAGAAAGCGGTTAACCACGGACAGAAACTGCTTATCATTC CTGGTCTTGATACTTATGTATATCCCTTGCCCCAGTCTATGCTTTTTTGGTTTAATCAAG TTCCAAATTCAGTTTTTTTAAGTGCACTGATTTGGATTTACTGTATTGAGTCAGCCAAAA GTAGTATTTGAGAAAGAAATCAAAGGACAAGAATAAAAAGCTCTGTCTCTGGATAAAGAT AAGGAAAGTAAGATTCAAAGAGGCTAAGTGGACTGTCCAAGGTCATGTGACTGTCGAGTG CTTGAGCCATGATTCCAAGTGAGGGCTATGTGACTTCATACTTTTTCTACGACATATTCC TGCCTATCACTACCCAGTAAGCTTTTTATCCTAGTAAGAATAAAAGAATACAGAATGACA TCTTTAAATCAGCAGATATAACTAAACCTAGCCAGTAAAAATATCAGGATGAAGAGAATA CACTGCAAAAAGATCACTTAAGATTCTTCAAATGATCACGTGAGCAATGAAAGTGCTTCC ACATAATAGAGGACTGTCCTCAGGGGAGAAATATTCCAGTAAGACACTGGATTTAAGATA TCAGTTCAACCTAGCATTTGCTATAAATCAGCATGTCCCAAACTGTATTCTCAGAACACT AGTCCTACAGGGTGATTCCCAGAAAAGGAGGCTATGGAGAAATAAGTTCAAGAAACACTA CCTACTGTATTTCAGGTGTATAGACTATTAGAGAGTATGGAGTATTGAACAAATGTTTAA CTCAGTGTTTCCTAAATTATAATCCTTTTTATGGGTCTCAATGAGTCCCATAAACTAGCA CTTCAGAGAACACACTTTGGAAAATGCTGTGTAACTATTCCCAAAAGTTACGACGTAAAG AACCACTGCTGTCCAAAAGATTCACAAAATGCTGACTATTGTTCGTAAAGTTATCATGAA CAAAACTGAAAATACTATCCTCCCCTTACATAAAACTGTGGAACTCATGGAATATTCTAT AGCAGTCTATAAATATTTTAGAACCCTAAGAAAAATACAAAGAGACTAAAGAAGGTCTGA GGCATGCTGATTAAATTTAACAGGAAGAAAAGAGACTAGTGCATTAAAACCTTAAGTATT AGACAAAAGGGCATCTCTGGTCAGAGTTGGAAACAAGTAACTTCTGGACAAATGGAAATA GAATTTAATTATGTGGGCTGTATATGTAGGGAGTTAATCTAAAAAGTAATATGAGCAGAA AACATAGATTCCAAAGAAAGTGATTAAGATACAAGATTCCTAATGCTATACTCAGAATGA TAAAAATAATAGCTGGCTGGGCGCGGTGGCTCACGCCTTTACCCAGCACTTCGGGAGGCC AAGGTGGTTGGGGATCGCTTGAGGCCAGGAGCTCGAGACCTGGACAACATGGTAAAACCC CATGTCTACTAAAAATACAAAAATTAGCCGGGCGTGAAGGTGCATGTCTGTAGTCCCAGC AACTCAGGAGGCTGAAGCATGAGAATTGCCGGAACCCAGGAGGCAGAGGTTGCAGTGAGT CAAGATCACACCGCTGCAATCCAGCCTGGGCAACAGAGTGAGACTCCATCTCAAAAAATA AATAAATAATAGCTAACATGCATTGAGTACTTGCAGTATCCCAAGACTTCACATGGATTA ACTCATTTAATTCAAGAATTCAATGAGACATTATTATCCACATTTTACAGATTTGTAATC TGATGCTAAGAGAGGTTAAGTAGTAAACTACCTAAGGTCACACATCTAGTAAACTGGTAG AAACAAGATGCAAAGGTACCTGAGCCCTGGGCCCACACTCCAGTCAATCCTGCCTTCTTA GCCTCTGGAGGTTGTTCTTCAGAATCTTTGTCCCAGGGACAAGAAATGGTCTGAGTGAAT AATAGATTATACTTTCTGTGACATTTCCTTTGCCTGTATAATCTTAGGATGGTTTTTATG CATTTTCTACATATCAGAATGTTCTTTTTTTTTCTCTCAATAGGAAAGAGAAGTAATTCA AGAAAGAAATAGAAACTTCAGGCAGAACATCCATTCATTCATTCATTGGATTGTATATCA TTGTTGCACAATCAGAATTGATAAGCACTGTTCCTCCACTCCATTTAGCAATTATGTCAC CCTTTTTTATTGCAGTTGGTTTTTGAATGTCTTTCACTCCTTTTAAGGATAAACTCCTTT ATGGTGTGACTGTGTCTTATTCATCTATACTTGCAGTGGGTAGATGTCAATAAATGTTAC ATACACAAATAAATAAAATGTTTATTCCATGGTAAATTTA OMIM ID 178990