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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP9 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4318 Official gene symbol MMP9 Full name matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) Aliases ,CLG4B,GELB,MANDP2,MMP-9, Gene summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq] Location Chromosome: 20   Locus: 20q11.2-q13.1 Gene position 44637547 - 44645200  Map Viewer Gene orientation plus Gene size 7654 bp Gene sequence >MMP9:14833639..14841292:Length=7654 AGACACCTCTGCCCTCACCATGAGCCTCTGGCAGCCCCTGGTCCTGGTGCTCCTGGTGCT GGGCTGCTGCTTTGCTGCCCCCAGACAGCGCCAGTCCACCCTTGTGCTCTTCCCTGGAGA CCTGAGAACCAATCTCACCGACAGGCAGCTGGCAGAGGTGGGCAAACACCTAGTCTAGAG TTGGGGAGGGCTGTCCGTGAGGGTGTTGAGTGTCCCAGAGAGGATGCAGGGCCTCAGAGG AGATGCTTTAGGGGTGTGTTGGTGGTGATGGGCGTATCTGAAGAACAGAGGTGTCCAGGG TTAGGCAGTGGGGGGTCTTGTGGAGGCTTTGAGCAGTGATGGCCAGAAATGGGCAATGGG GCTTTCCTAGGTGGGAAATGGGAAATGGTTTGGGGTGGGGGAGGCATTGGAGGGTTCTGG GGTAAGCATAGGCTGGGAGTGAACAGGGGCAAACCTTATGCAGCTGTGGGGTAGAAATGG GCTAGAGGCATCCAGGGGTGAGAAGGAGCTGAGGATGTCTAAGGAGGGGAGATCCCTGGG TGGTCAGAAAGCACTGGTGTCTGGAAAGCATTTAATGCTTTATTAAATGTTAGTCCCTGC TGGGCATGACGGCTCACACTTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGTAGGATCG CTGAAGCTCAGGAGTTTGAGCCCAGCCTAGGCAACATAGTAAGATCCTGTCTCTACAAAA AAATTAAAGAAATAGCCAGGCACAGTGATGTGCACCTGTAGTTCCAGCTATGCAGAAGGC TGAGATGGGAGGATCGCTTGAGTCCAGGAGGTCCAGGCTGCAGTGGGCTGATACCGTCTC TCCGAAAAAGAAAAAGAAAAAAGACTCCCTCCATGAGTGTCTGGAGGGAGTCCTTTGGCC CCAGCTGGGCAGAGAAAGGGGTCAGAGATCTGGCATGTGTGTGTCCCTTCATCCACAGGA ATACCTGTACCGCTATGGTTACACTCGGGTGGCAGAGATGCGTGGAGAGTCGAAATCTCT GGGGCCTGCGCTGCTGCTTCTCCAGAAGCAACTGTCCCTGCCCGAGACCGGTGAGCTGGA TAGCGCCACGCTGAAGGCCATGCGAACCCCACGGTGCGGGGTCCCAGACCTGGGCAGATT CCAAACCTTTGAGGGCGACCTCAAGTGGCACCACCACAACATCACCTATTGGTGAGCCGG GGCCGTGGGGGCAGCGGGGTGGGGCGGGGAGGCCAGGTCTGGCTCTTGGGCCAGCGGTGA ACATGTCCTGTCTTGGACGCGTCCCTGGGTTTCACTATTTAATGTGTGGCCCCTGGGGAG TGTCCCCACCTCTGAGCCTCTGTTTCTCCTTCAGGGAAATGGCTCTTGCAATCCAAGTCC TCCTGCCAGGGCCATTGTGAGGGTCTAAGTAGACAAAAAAAAAAAAAAAAAAAACAGTCT GGAAGCAATTTATAGATGAGAGCGTGGACGGCAGAGAGCATTGTGTATGTTGAAGTCTCT GCGATATGGGGTGTCCCTGCTGCCCCGCTCCAGCCTTTCACTTCTGACCTCCTTCCTCTG GCTCTTACGCTACAGGATCCAAAACTACTCGGAAGACTTGCCGCGGGCGGTGATTGACGA CGCCTTTGCCCGCGCCTTCGCACTGTGGAGCGCGGTGACGCCGCTCACCTTCACTCGCGT GTACAGCCGGGACGCAGACATCGTCATCCAGTTTGGTGTCGCGGGTGAGAACGTGAGGAG GGAAAATCCAAGAGACCTGGGCGGGGTCAGGGAAGGGAGGACCACGGAGAGCGTGGAGGC AGCAGTGGCCCCGGCTTCCTCTTGCCTGCCCGCGCTGCCCTGGCTTATACGGCCCCTCCT GCCAGACAGTGCACAGGGCCAGGGCGCCAGGCTGGGAGAGCTTCGCGCAGGCGGGATTTC AGCCCGCACTTATTTCGGAGCCCTTGCCTTGGGCAGCGCACAATCTGCGCAGCAGTACTC GGCTAACCCTCTTCCTCTCGACCTGTTTCTTCAGAGCACGGAGACGGGTATCCCTTCGAC GGGAAGGACGGGCTCCTGGCACACGCCTTTCCTCCTGGCCCCGGCATTCAGGGAGACGCC CATTTCGACGATGACGAGTTGTGGTCCCTGGGCAAGGGCGTCGGTGAGATTCTGAGTCCT CCTGGCCCCTGATTCCCTTCATTCTCTCCCACTCATCACCCGCCGCCCTAACTCCGGTCC CCCCTCCTCCTGCAGTGGTTCCAACTCGGTTTGGAAACGCAGATGGCGCGGCCTGCCACT TCCCCTTCATCTTCGAGGGCCGCTCCTACTCTGCCTGCACCACCGACGGTCGCTCCGACG GCTTGCCCTGGTGCAGTACCACGGCCAACTACGACACCGACGACCGGTTTGGCTTCTGCC CCAGCGAGAGTGAGTGAGGGGGCTCGCCGAGGGCTGGGGGCGCCCACCACCCTTGATGGT CCTGGGTTCTAATTCCAGCTCTGCCACTAGTGCTGTGTGGCCTGCAATTCACCCTCCCGC ACTCTGGGCCCAATTTTCTCATCTGAGAAATGATGAGAGATGGGATGAACTGCAGACCAT CCATGGGTCAAAGAACAGGACACACTTGGGGGTTATAATGTGCTGTCTCCGCCTTCTCCC CCTTTCCCACATCCTCCTCGCCCCAGGACTCTACACCCAGGACGGCAATGCTGATGGGAA ACCCTGCCAGTTTCCATTCATCTTCCAAGGCCAATCCTACTCCGCCTGCACCACGGACGG TCGCTCCGACGGCTACCGCTGGTGCGCCACCACCGCCAACTACGACCGGGACAAGCTCTT CGGCTTCTGCCCGACCCGAGGTACCTCCACCCTGTCTACCAGGTTCAGCCCCGCCCTCTC ATCATGTATTGGCCCCCAAAACGCGGCTCTTCCCTCCCATCAGTTTGTCTTTCCACTCTC ATTGGTCCTCAGGACGACCGTGACTCCGCCCACCTACACCACATTTCCACCACTATCCCT GACTTCCAATGGCCCCGCCCCAGCCACTAAGGTTCGGCCTTTTCTGCCCAGCTGGCCGCC TCTTCCTTGGTCTGGTGTCCCAGGCACCGCCCACGGGTCTAGCCTCTTCTCAGGAGTGCT CTACAGCGCCCCCTAGGCCACCAAGATTGTTTAGCTCCCTGTCGGGTCGGCCCCTGACTC CTTATTGGACTCATCCATCTGGCTCATCCAAGGCCTTGGGTCTCTCCAGCTGACTCGACG GTGATGGGGGGCAACTCGGCGGGGGAGCTGTGCGTCTTCCCCTTCACTTTCCTGGGTAAG GAGTACTCGACCTGTACCAGCGAGGGCCGCGGAGATGGGCGCCTCTGGTGCGCTACCACC TCGAACTTTGACAGCGACAAGAAGTGGGGCTTCTGCCCGGACCAAGGTAGGCGTGGTCCC GCGGCTCCGGGGCTGGGGTTCCCGGCAGTGGTGGTGGTGGGGTGGCCAGGGCTGGGGGCT CGGCCCGGCGCTCACGTCTCAGGCTCCCTCTCCCTCCAGGATACAGTTTGTTCCTCGTGG CGGCGCATGAGTTCGGCCACGCGCTGGGCTTAGATCATTCCTCAGTGCCGGAGGCGCTCA TGTACCCTATGTACCGCTTCACTGAGGGGCCCCCCTTGCATAAGGACGACGTGAATGGCA TCCGGCACCTCTATGGTGAGGCAGGGGCAGGGATGGGAGGAGGAGGGGAAAGGGCGTGGC TGTGCCACAGTACCAAAGAATTGGGGGTTGGGGATCGGGGGAGGAACGGGGCGTGCAGGA GAGGTGGGACCTCAACGTCTGTCTGGAAGCAGAGCCTGGGCCCAGTCGCTGCCATGTCAG TGCTTAGAGGTGGTGATAAAGAGACTCTAGAGAGAGATAGGTGTGACTTCAAAAGCCAGT CTACTCTGGGCATGGTGGCTCACGCCTCTAATCCCAGGGCTTTGGGAGACCCAAGGCGGG AGGATTGCTTAAGCCCAGGAGTTCCAGACCAGCCTCGGCAACATAGCCAGACTCCCATCT CTACAAAAAATAAATGAGCAAGGCGTGAAGGCACATGTCTGTAGTCCTAGCTACTCTGGA GGCTGAGGTGGGAGGATCTCTTGAGCCCAGGAGTTCGAGGCTGTAGTGAGCTATGATTGC ACCACTGCATTCCATCCTGGGCCATAGAGGATGTCGCTTAAAACGAAAAAGAAGAAGAAG AAAGTCCTGTGGTTTGGGAAGGGAGGCTGAGTGAGGAGGGGCCTGTGTGCCAGAGGAGGC TTCACTGAGAAGCTTAGGGGAGCAGATGTTCTAGGGGTACAGAGGTATGCAGGAATAGGA AGAGTCTCACCCCGTGTCTCTTTTTAGGTCCTCGCCCTGAACCTGAGCCACGGCCTCCAA CCACCACCACACCGCAGCCCACGGCTCCCCCGACGGTCTGCCCCACCGGACCCCCCACTG TCCACCCCTCAGAGCGCCCCACAGCTGGCCCCACAGGTCCCCCCTCAGCTGGCCCCACAG GTCCCCCCACTGCTGGCCCTTCTACGGCCACTACTGTGCCTTTGAGTCCGGTGGACGATG CCTGCAACGTGAACATCTTCGACGCCATCGCGGAGATTGGGAACCAGCTGTATTTGTTCA AGGATGGGTGAGGAGGCGGGGTTGTGTGGATGCGGGAGGGGGCTTTGCGGAGGGGCTGCC CGTCCCTTCCCGCCCACTGGCCCTGTGTCCAAGGCTTAGAGCCCGTCCTTTCCCTCCTCG CTTTCTCAGGAAGTACTGGCGATTCTCTGAGGGCAGGGGGAGCCGGCCGCAGGGCCCCTT CCTTATCGCCGACAAGTGGCCCGCGCTGCCCCGCAAGCTGGACTCGGTCTTTGAGGAGCG GCTCTCCAAGAAGCTTTTCTTCTTCTCTGGTTAGTTACCTACTTTCCCTCCCCCGCCCGG TCAATCCCCATCAGTCAAGGAGGCTCAAGAGACCATCGATAACCCACGAAACGTCTTGTG CGTTTTAGAAAAATACGCCCCCTGGCGGACGCAGTTTAGCAAACGTAGGGGCGGCTGAGT TTCTGCCCCCTCCTCTCCACGCCCTCGCGTCGCTCTACCCAGCGCCTCTGCCCCTGGGTT GCAGGGACTGCGGGCACGCGGGCTAGGAAAGGCCTCGCCGGAATCTCCCTCCTCGCGTTC TAGGAGTACGTGCTCCCTCTGCGCCCCCAAACCGACGTGACCCTCCTCCCCTGCAGGGCG CCAGGTGTGGGTGTACACAGGCGCGTCGGTGCTGGGCCCGAGGCGTCTGGACAAGCTGGG CCTGGGAGCCGACGTGGCCCAGGTGACCGGGGCCCTCCGGAGTGGCAGGGGGAAGATGCT GCTGTTCAGCGGGCGGCGCCTCTGGAGGTGAGCGCCGCCGCGGCCGCCGGCAGGGGGAGC CCGGGCGCCGTCGGTCCGTCCGCTAGCCGGCTCAGCACCTGTCTCCTCCGCGCCTGCCCG CAGGTTCGACGTGAAGGCGCAGATGGTGGATCCCCGGAGCGCCAGCGAGGTGGACCGGAT GTTCCCCGGGGTGCCTTTGGACACGCACGACGTCTTCCAGTACCGAGGTGAGGGCTGAGG AGGATCCCTTCGTGAGACACCACACTAAGCTCCTCTTAGTGAGTGGTCAAATTCTGAGCG AGGAAGAAAAAGCCCTTGGAAATGGAAACAAATGCCCCAGCACAGACAAGATCCCAGCAG AGGCAGAGGCCTTCTCCAGGTCATTTAGGAAGTCAGGGATGCAACCAAGACCAGGACCCA GATTTCCTGCCTCCCCGGCTGGAAGCTCTTTCTCCTTCAGTACAGGACGGCAGGTGGTTT GTATGGAAGCTCAGTTATTAGACAACAGTCATCAAGTGCCGATAATGTGCCAGGCACTGT GCTACAGGGAGAGATAAGACAATTCACAGCTCTGTGACTTTGGGCAAGTCACTGCTTCTC TACTCTTCGAGCCTCAGTTTCCCCATCTGTAATATGGGGACTATAGCTGGAATTACACTT GACTTCCCTTTCTTACCAGTCACATCCAAACAGTTGACAAGGTGAACAAGATTTCCTGCC ACCAAAATCTTTTTCGAGTCTGTCATTTTTTTTGCCATCTTCTTTATAAACACCCCAGCC CAAACCATACTGGCTGTCCAGGACCTTTAACAAATTCCATGAGATTAGAGAGGGGGTAGG AGTGAAGGGCAATGGTCTTGGGAGTGACCCCAGATGAATTCCAAGGTCAAAGAAATTAAG AGGATCTGACACTCCACCCCCGTGTTCTCATCTCTTCCCACTCCTCCTGTTATTTACTCT GCTCCACCCACACTGGCTGCTCTTTGAACAGATCAAGGTCATTCCTAGCTTACAGCCTTT GTGCCAGTTGTTCCCTCTGTCTGGAAAGCTTCCCCTCCAGATTGTCACTGGGCCATCCCA CTGTCTTCCTTCAGGTTTCAGTGCTAAGGCCATTGCTTCAATGAGGCCTTCTTTGATGCT TATTATCTATTTACTTGTTTTTATTTTCTCCATAGCTTTCTATATTTTCTTTTTTTTTCT TTTTTCTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAG TGGCACGATCTCAGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCCTC AGCCTCCCAAGTAGCTGGGATTACAGGTGCCTGCCACCACGCTTGGCTAATTTTTTGTAT TTTTTAGTAGAGACGGGGTTTCACCATCTTGGCCAGGCTGGTCTTGAACTCCTGACCTCG TGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCCA GCCGCTTTCTATATTTTCAAAACCAATCTCATTTATTTATGTGTTTGCTTAATTGTCTCT TGCCTCACTAGAGTGTAAGCACCAAGATAATTGAGATCATGCCTGCATTTTTTCTGCTTA TCCCCAGTATCTTGAACAAAGCACATAGTAGATGCTCAGTAAATGATGAATGAACAGATT TGTTCAATGAATGAGCGTTGAATGAATTGTTCTGAGCATTAAGATAGTTGGTCTATTCAT TTGTTAATTCATTCACAAAATGTGTATGGTGTACCTACTGTGTGCTAGGCTCTGTGGCAG TGCTTTGGGCACTGAGGTCTGTGCCCTCCAGCATCTCACAGAACCTCACAGCATCTCACA GGTTGGGGGGATGGAGGTGATATGTGAAAACCTTAGAAAGTTCTAGAAATGGCAGAAGAG ATGGTTGTCAAGATCTTGTTCCTATTTCTGTATATGTGGGAGAATTAGAATCACTCCTCT TATGCCTGCCTGTCTCCTGCAGAGAAAGCCTATTTCTGCCAGGACCGCTTCTACTGGCGC GTGAGTTCCCGGAGTGAGTTGAACCAGGTGGACCAAGTGGGCTACGTGACCTATGACATC CTGCAGTGCCCTGAGGACTAGGGCTCCCGTCCTGCTTTGGCAGTGCCATGTAAATCCCCA CTGGGACCAACCCTGGGGAAGGAGCCAGTTTGCCGGATACAAACTGGTATTCTGTTCTGG AGGAAAGGGAGGAGTGGAGGTGGGCTGGGCCCTCTCTTCTCACCTTTGTTTTTTGTTGGA GTGTTTCTAATAAACTTGGATTCTCTAACCTTTA OMIM ID 120361