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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ASGR1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID432
Official gene symbolASGR1
Full nameasialoglycoprotein receptor 1
Aliases,ASGPR,CLEC4H1,Hs.12056,
Gene summaryPartially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.[provided by RefSeq]
LocationChromosome: 17   Locus: 17p13.2
Gene position7082883 - 7076750  Map Viewer
Gene orientationminus
Gene size6134 bp
Gene sequence
OMIM ID108360