Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP16 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4325
Official gene symbolMMP16
Full namematrix metallopeptidase 16 (membrane-inserted)
Aliases,C8orf57,DKFZp761D112,MMP-X2,MT-MMP2,MT-MMP3,MT3-MMP,
Gene summaryProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q21.3
Gene position89339717 - 89049460  Map Viewer
Gene orientationminus
Gene size290258 bp
Gene sequence
OMIM ID602262