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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP17 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4326
Official gene symbolMMP17
Full namematrix metallopeptidase 17 (membrane-inserted)
Aliases,MT4-MMP,
Gene summaryProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24.3
Gene position132312941 - 132336316  Map Viewer
Gene orientationplus
Gene size23376 bp
Gene sequence
OMIM ID602285