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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MNDA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4332
Official gene symbolMNDA
Full namemyeloid cell nuclear differentiation antigen
Aliases,PYHIN3,
Gene summaryThe myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q22
Gene position158801168 - 158819270  Map Viewer
Gene orientationplus
Gene size18103 bp
Gene sequence
OMIM ID159553