Entrez gene ID | | 4335 |
Official gene symbol | | MNT |
Full name | | MAX binding protein |
Aliases | | ,MAD6,MXD6,ROX,bHLHd3, |
Gene summary | | The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17p13.3 |
Gene position | | 2304258 - 2287354 Map Viewer |
Gene orientation | | minus |
Gene size | | 16905 bp |
Gene sequence |
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OMIM ID | | 603039 |
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