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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ASIP (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 434 Official gene symbol ASIP Full name agouti signaling protein, nonagouti homolog (mouse) Aliases ,AGSW,AGTI,AGTIL,ASP,MGC126092,MGC126093,SHEP9, Gene summary In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. [provided by RefSeq] Location Chromosome: 20   Locus: 20q11.2-q12 Gene position 32848171 - 32857148  Map Viewer Gene orientation plus Gene size 8978 bp Gene sequence >ASIP:3044263..3053240:Length=8978 GCCTCCTGGGATGGATGTCACCCGCTTACTCCTGGCCACCCTGCTGGTCTTCCTCTGCTT CTTCACTGCCAACAGCCACCTGCCACCTGAGGAGAAGCTCCGAGATGACAGGAGCCTGAG AAGCAACTCCTCTGTGAACCTACTGGATGTCCCTTCTGTCTCTATTGTGGGTAAGTCACC TAGCCTCTGGGCTCTGGCCCAGGAGAGGGGCTGCAGGAGATCAAGCATGCTTCCCAGGGT GCTACCAGGATCCACCGCCATGGTCACGGCTCCTTCTTGCTCGTTCCAGGAAATAATCCT GGGAGAATAAGGTGGCCCTTGACTCATTTGGTTTGGGAAAGCTCTGCATGCCACCAGTCT AATAAGCAGCTTAGCATATGGTAGAGGCTCTGAAAGGCCTGAAGTTAAGACACTTGGTGA ACTTTGTTTAATTTAGCATTTCTGAAACTTAATGAATCACAGAACTCCTGTCAACAGTAA CAAACTTCAGGAAATGCTCCAGAACATATGCAAGTCTGGGATGGACCAGTCCTGTCATGT CAGGGTTGGGAATGAAGGCTCAGGGGAAAATATGAGGGGCACTGGAGCCTGGCATTGGAG ATCTGGTTTGACTTCACCTGATAATAATCATAGACATACTGTGTGGTAGGCACTGTGAGG TGAGTATGGTCTTTATTCATATTTCACAGTTGAGGAACTTGAGGCTTAGGAGAATTAAGT AACTAGCACGGATCACACAGTTTTTAACTGGCAAAGCCAGAATTCAAAATCAGGTACTTA ACTCCAGAACCTAAGCTCAAAACTAATATCTCTTACTACCTCGGCTTTTGCTAGGAAACG AGGATATTTGAGGCTGGGTGAGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAAGCTG GAGGCATGAGGATTGTTTGAGCCTAGGAGTTCAAGACCAGACTGAGCGACATAGGGAGAC CCCGTCTCTACAGAAAAATTTAAAAACTAGCAAGGCACGTGGCATGCACCTGTAATCCCA GCACTTTCGTAGGCTGAGGCGGGCAGATCTCTTGAGCTCAGGTGTTCAAGACCAGCCTGG TCAACAGGGTGAAACCCCGTCCCTATTAAAAATACAAAAATTAACCAGGCATGGTAGCAT GCGCCTGTAGTCCTAGCTACTTGGGAGGCTGAGGCAGGAGGATCACTTGAGCCCAGGAGT TTGAGCCTACAATGAGCCATGATTGTGCCACTGCACTCCAGCCTGAGTGACAGAGTGAGA TCCTGTCTCAAAAACAAACAAACAAAAACTAGCCGGGAATGGTGGTGCATGCCTATGGTT CCAGCTATTTGGGAGGCTGAGGCAGGAGGATTGCTTGAGCCCAGGAGGTCGACGCTGCAG TGAGCTATGATCACACCATTGCACTCCAGCCTGGGTGACAGACAGACCCTGACTCAAAAA AGAAATTTTTTAATAAATAAATAATCGGCCAGGCGCGGTGGCTCACACCTCTAATCCCAG CGCTTTGGGAGGCCAAGGTGGGCAGATCACCTGAGGTCAAGAGTTTGAGACCAGCCTGGC CAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGTACA TGCCTGTAATCCCAGCTACTTGGGAGGCTGAGACAGGAAAATCACTTGAACCCAGGAGGC AGAAGTCACAGTGAGCCGAGATCGCACCACTGTACTCCAGCCTGGGCAACAGAGTGAGAC TCTGTCTCAAAAGAAAAAAAAAAGAAGAAGAAGAAAGAAAGAGGATATTCTACACATATC AGACAGGGAAGGGAGGAACATCAACATTTATTGATCTTCAGTGTAACAGACTTTTCACTT TATAAACAGACTTCATTTATCCTCAAGACAATACTGCAAGGCAGATATTATGGAACCTTT TTTGCAGATGAAAAAACTGAGTCTCATGGAGGATAAGTAAGTTACCCACAGCCACATAGT CATTATATTGGCAGAGTCAGGATTCAAATCAGGTCCTCCTGGCTCCAGAGCTCTCAGGAA TGGAAAATAGGAAACACAGGTGCATCTGTGTACAAGACAGGAGTCCATTTTCTGGGTATC ACAATGTTCCTGTGCCTGCCACAATGGAGATGAAGGAAGGGGCACCTGGGGTGGCTCTGA GTGGCCCAAGCTCACTTAGGTCGAGGGACCAGGCCCCACAAGAGTGTCACAGGCAGATCC CAGTGCCTGCTTGGATTTCCCATTTGCCTTCCCTCAGAGGACACGTTGCTATCAGTGCCT GGCTCCAGGTCAGTAGCCGGGCTAACAAGAACCTACTGGCTTGAGTCCTACAGTGTGACT CATCCAGCACGCTTCTTCTCCTCTCCCTGACCTTGTGACTTCCCAAGCCCCCTCTGCCCC TCTCACTTCACTGCAGCTCAACGTCCCCAGAAACATCTGACTTTGCTCCTTTTGTCTCTC TTTGAAGCGCTGAACAAGAAATCCAAACAGATCGGCAGAAAAGCAGCAGAAAAGAAAAGA TCTTCTAAGGTAAGGGCAGGGAAGTTCTGGGAGTTCTCATTGTTGGGGTGAGACTGGACT TAAAGAAGGAGGACCCCCAACCTCTGGCTAGGAACTAAATGAAAGATTTTTCAGGCCTAT ATTAACAAAAGAAACTGAAAGCTACTAAAGACTTCCTGGCTTGAGCTCTGAGCCAGACAC CCACAGAAGCCCAGGGAGCTGAAGTCCACTGAGCAAAATAGGTTACGAAAAGCAGCTTCC TCTACTAGTTAGCCCCTGCCTGAAATTTCACCATCACTCATACTTTTGGATGAATGTGGT GTTTCCCAAACCTCAGTCATTTCAGAACCACATTTATAACTTTGCCATATCTGAGTTCCA CCTATTTATTTAACATATTTGTTTAAAATTAAATCTTAGGCCGGATGCGGTGGCTCACGC CTATAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGAATCACCTGAGGTCAGGAGTTCGA GACTAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGG CGTGGTGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTG TACCCGGGAGGTGGAGGTTGCAGTGAGCTTGAGCCATTGCACTCCAGCCTGGTGACAAGA GTGAAACTCTGTCTCAAAACAACAACAACAAAAAATTAAAACTTAAAAAATGCAGTTGAC TCTTGAACACATGTGTTTGAACTCATGGGTCCACTTATACATTGGTTATTTTATGTCTTT TTTTTTTTTTCTTTTTTTTTGAGATGGAGTTTTCGCTCTCGTTGCCCAGGCCAGAGTTCG GTGGCGTGATCTTGGCTCACTGCAACCTTCACCTGGCGAGTTCAAGCGATTCTCATGCCT CAGCCTCCCGAGTAGCTGGAATTACAGGCACATGCCACCATGCCCAGCTAATGTTTTTGT ATTTTTAGTAGAGATGGGGTTTCGCCAAGTTTGTCAGGCTGGTCTCGAACTCCTGACCTC AGGTGATCCACCTGCCTCAGCCTACCAAAGTGCTGGGATTACAGGGGTGAGCCACCTTGC CCAGCTGACTTTTTAAATTGGAAAATATTTTTGAAGATTGACAATTAGAAAAAACAGGTG AATCTTGTTACCTAGAAATATTTAAAAAATGAAAAAAAAGTATGTCATTAATGCATAAAA TATATGTAGATACTAGTCTATTTTATCACTTGCTATCATACAATATACATAAATCTATTA TAAAAAATTAAAATTTCCCAAAACATATGTACACACAGACAGTACATACCATTCAAAATA GAAAGAAAATAACCAAATGTAAAGATGTAGTACTAAATCATAACTGTGTAAACAACTGCA GTACATACTGTACTACCATCATAATTGTGAAGATACCTCCTGTTGCCATTGCGGCATGCT CAGGTGTTGCGAGTACGTGCTTACAACGCTCTGTGAGCTAATCATCTCTGCACAAGGAGT CTCACCAGGAAATCACATATTGCAGTAAAATGTGATCCCTCAAGGTTCTCGTGTATTTTT CAATGTGTTTAATGCAATATTGTAAACCTTGAGTAGTACCAAGGGACCCATACTAGGTGC TACTAGTGATTCTGGAAGTGTTCCCAAGAAGCAAAGAAGAGTCATGACATTACAAGAAAA AGTTGCTTGAATTACTTGATTGATACTATAGGTTGAGGTCTGAAGCTTTGGTTGCTTACT ATTTCAGACAGACAATACATCTTGTAAACAGATGAAGTAAACTTACGGTATCAATAAATA CAGTACAGTACTGTAAATGTATTTTCACTTCCTTATATTTTCTTATAATCGATCTCTACT TATCCAATAATTTTCTTAATATTTTATTTTCCCTAGTTTACTTCATTTTTTTTTTTTTTT TTTTTTTTAGAAATGGGGTGTCACTCTGTCACTCAGGCTGGAGTGCAGTGGCACCATCTC GGCTCATTGCAGCCTCAACCTCCCAGGCTCAAGTGATCCTCCTGCCTCAGCCCCACAAGC AGCTAGGACTACGGGTGTGCACCACCATGCCTGGCAGATTTTTGTATTTTCAGTAGAGAT GAGGTTTTGCGGTGTTGCCCGGGCTGGTCTCAAACTCCTGAGTTCAGGCAATCCGCTGCT TCTGTCTCCTAAACTGCTGGGATTACCTGCATTAGCCACCATGCCCAGCCAGTTTACTTG ATTATAAGAGTACAGTATATAATACATATAACATAAAAAGATGTTAATCCACAGTTTATG TTATCAGTAAGGCTTCCTTCTGGCCAACAGTAGGCTATTAGTAGTTAAGTTTTTGAGGAG TCAAAAATAATATGAGGGCCAGGCACGGTGGCTCACACCTATAATCCCAGCACTTTGGGA GGTTGAGGTTGGCAGATCACTTGAGTCCAGGAATTCAAGACCAGCCTGAGCAACATGATG AAACCTCATCTCTACAAAAAATTTAAAAAATTAACTGGGTGTGGTGGTGTGCTCCTGTAG TCCCAGATACTCAGGAGGCTGAAGTAGGAGAATCGCTTGAGCCTGGGATATCGAGGCTAC AGTGACTTGTGATCATACCACTGCACTCCAGCCTGGGCAACAGAATAAGACCCTGTCTCA AAGAAAAAAAGGATTTTTGACTGTGTGTAAAGAGTTTGTGCCCCTAACCCCTGCATTGTT CAAGGGTCAACTGTATATAATTATGATAGAAAACTAGTATCACTTACCATAAATAGAAGG TAACTATAAAAATAAGTAAAGTTGGCCGGGCACAGTGGCTCACACCTGTAATCCCAGCAC TTTGGGAGGCCAAGGAGGGTGGATCACCTTAGGTCAGGAATTTAAGACCAGTCTGACCAA CATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTATGGTGCTGCACGC CTGTAATCCCAGCTACTCAGGAGACTGAGGCAGGAGAATCACTTGAACCTGGAAGGCAGA GGTTGCAGTGAGCCAAGATCACACCACTGCACCCTAGCCTGGGCGACAGAGCAAGACTGT CTCAAAAAAAAACAAAAGCGGAGGGGGGGAAGTTAAAACATTGTTAGTAAATTCTGGGTG AATGGATGGTATTGCCTACCAAAGGCTCTAAATTTGAGGCCTAAATCTCTGTGTTAAAAG GCATAATGGCCAGGCACGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCTGAGGT GGGTGGACCACAAGGTCAGGAGATCAAGACCATCCTGGCTAACACGGAGAAACCCCGTCT CTACTAAAAATACAAAAATTAGCCGGAGGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTT GGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCAGAGTACAGTGAGCCGAGACC GTGCCACTACACTCCAGCCTGGGTGACAGAGCGAGACTCCGTCTCAAAAATAATATAAAA TAAAACAAAAAATAAAAGGCAGATTAGGCCAGGCACGGTGGCTCATAACTGTAATCCCAG CACTTCAGGAGGCTGAGGCAGGCAGATCACCTGAGGTTAAGAGTTAGAGACCAGCCTAGC CAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGCA CGCCTGTAATCCCAGCTACCTGGGAGACTGAGGCAGGAGAATCACTGGAACCCGGGAGAT GAAGGTTGCAGTGAGCCGAGATGGCACCACTACACTCCAGCCTGGGTGACACAGCAAGAC TCCATCTCAAAAACAAACAAACAAACAAACAAAAAAGGCAGATTATAAAGTGTTAGAAAG GCACTAAGGACACGTTAGCACCAAACTGACCCTTTCAAGTTGAAAAAGATTGAAAAAAGA ATCCTTTTTTATTGTATAATTCAGGATCATTTAACATTCACGTACCACCTAAAATCATAC CACCATTAACACAGGTTCCCACTTTGGGAAATACTGGACTGAGGCATTGCTGAAATGCAC ACCTTATTCCTGTCTTAGTGTGCCTCAGTTTATCATATCAACTGTAACCAAAGCAAGGAG CACTGGATTAGGTATTAGGAGGTAGGATCTGGCACTGTGTGATCTTGAAAGTCCCTGCTC TTTTCTAGGCCTATTTTGTTGGCTGTAAAGTGAACAAGCAAGATGAGATTATTGACAGAT AAAAATATATAACTGACAAATATATTTATATGCTAAGCACTGGGAACATAGCAGTGAATA AGAAAGATATATCTTATCCTTGGTCTCATGGAGTTTACATTCTTGTGGAGAAAACAGGTG AACAGCAAGTAAATCAATAAATAGGTAAATAAATTCAGATGTTAAAGAGTGCAAAGAAAT TACAGCACGGTAATGAGACTGAAGGGAAGAGTGGTCTGGGAAGGCCTCTGTAAGGAAGTA GCATTTAAATAGAGTGAAAAACTCAGTAACCTAGAGCAGCAGCGTCCAATAGAAATACAA TGTGAGGCCAGGCGCGGTGGCTCACATCTGTAATCTCAGCACTTTGGGAGGGCGACAAGA GTGAAACTGGCTCTCAAAAAAAAAAAAAAAAAAAAAAAAGAACTGTGATGTGAGCTACAT AATTTTAAATTTGCTTATGGCCACTTTATTTATTTATTTTTTTTGAGACAGAGTTTTGCT CTTGTTGCCCAGGCTGGAGTGCAATGGCGCAATCTCCACTCACAGCAACCTCCACCTCCC CGGTTCAAACAATTCTCCTGCCTCAGCCTCCCGGGAGTAGCTGGGATTACAGATGTGCCA CCATGCTGGGCTAATTTTTGTATTTTTAGTAGAGACGGGTTTCTCCATGTCGGTCGGGCT GGTCCCAAACTCCCGACCTCAGGTGATCCGCCTGCCTAGGCCTCCCAAAGTGCTGGGATT ACAGGCATGAGCCACCACACCCAGTTGATAACCATATTTAAAAAAAAAAAAGGTGCAATT AATTGTAATATTTTATTTAACCTAGTGTATTCAAAATGTTAACATTTCAATATGTGATTA ATTTAAAAAGTTATTGAAATAATTTATTTTTGTTGTGCTAAATCTTTGAAATCTGGTGCA TAGTTTACAGCACATCTCATTCCAATGCTCAGTTTTGACAAGCATAAAATGTAGTTCTAA CTAAAAAGTTGTGTTTAAGAGGAAGAATATTTTTATATTGCTTCAGTTTTACATTTTAAA TTTAAATTAATTAAAATTAAATTTGAAAATTCAGTTTCTAGGTTGCACTAGACACATTTC ACGTACTCAGTAGCCACAGATGACCAGTGGCTACCTGTATCGAAGGTACAAAAACCAGTG GCTATTTCCTTCCCAGGAAAAGAAGCAGCAAGCTGTGGCAGCAGTGTCCAAGACAGCTCC TGCTGGGTTCCTGCAGCAGGAACTCACCTGCTGCGTTCGGTGCACAGCGGGGCAGCGAAG TTAACAGGGGTCGGAGAGGCAAGCAAGGGCCAAATCTCAAAGGCCAAAAGAAAGTTCATG TTTCATTTTAAGTTCAAAGAGAAACCACTTAGGCCGGGCGCGGTGGCTCACGCCTGTAAT GTAAACCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCACTTTAGCTCAAGAGTTTGAGA CCAACCTGGACAATAAGTGAGACCCCGTCTATAAAAACATAGAAAATAAAATAAAAATAA ATTTAGCCAAGCGTGGTGGTGCGCACATGTGGTCCCAGCTACTTGGGAGGTTGAAGTGGC AGAATCGCCTGAGCCCGAGATCGAGATTGCAGTGAGCCGAGATCGCGCCACTGCAGTCCA GCCTGGCTGACAGAGTGAAACCCTGTCTAAAAAAAAAACAAAAAACAAACAAACAAAAAA AACACAAACTAGGGAGAAGACGACCAGGGCCAGGCAAGAGCCAGGTAAGTCTGGATGGGG ATGGAGGTGAGGGAATCTGACTGGGGGAGCGGGCGGTGGGCGGTGGGCAAGCCAGCGGGG AAACCTCTGGTCCGGGATCTCCCTAGCCCGAGGAGCTCCCAGGCAGAGGTGAGGACCGGA GGGGTGGGCGTGGCCGGCTCATAAAGCCCCGGCGTTTCCCACGCAGAAGGAGGCTTCGAT GAAGAAAGTGGTGCGGCCCCGGACCCCCCTATCTGCGCCCTGCGTGGCCACCCGCAACAG CTGCAAGCCGCCGGCACCCGCCTGCTGCGACCCGTGCGCCTCCTGCCAGTGCCGCTTCTT CCGCAGCGCCTGCTCCTGCCGCGTGCTCAGCCTCAACTGCTGAGCGCCCCCACTCCCGGC CGCGAGCAGGCAGGGCTTCGGGGACGCGGGGCGCTTCTCGGGCGGGTGATCCCTAACAGG GCGGCTTCCCAGGGCTGCAGGCGGGCGGAGGTTCCAGGAGATGGGACTTCAGGGAGACCT GGCTTGGGCTAAAATCGAAATACAATATATATAGGCTG OMIM ID 600201