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Gene information for MSH3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4437
Official gene symbolMSH3
Full namemutS homolog 3 (E. coli)
Aliases,DUP,MGC163306,MGC163308,MRP1,
Gene summaryThe protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q11-q12
Gene position79950294 - 80172634  Map Viewer
Gene orientationplus
Gene size222341 bp
Gene sequence
OMIM ID600887