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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MSH5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4439
Official gene symbolMSH5
Full namemutS homolog 5 (E. coli)
Aliases,DKFZp434C1615,G7,MGC2939,MUTSH5,NG23,
Gene summaryThis gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms heterooligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p21.3
Gene position31707725 - 31730455  Map Viewer
Gene orientationplus
Gene size22731 bp
Gene sequence
OMIM ID603382