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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MST1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4485
Official gene symbolMST1
Full namemacrophage stimulating 1 (hepatocyte growth factor-like)
Aliases,D3F15S2,DNF15S2,HGFL,MSP,NF15S2,
Gene summaryThe protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p21
Gene position49726196 - 49721380  Map Viewer
Gene orientationminus
Gene size4817 bp
Gene sequence
OMIM ID142408