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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MTNR1A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4543
Official gene symbolMTNR1A
Full namemelatonin receptor 1A
Aliases,MEL-1A-R,MT1,
Gene summaryThis gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q35.1
Gene position187476537 - 187454809  Map Viewer
Gene orientationminus
Gene size21729 bp
Gene sequence
OMIM ID600665