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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MUC1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4582 Official gene symbol MUC1 Full name mucin 1, cell surface associated Aliases ,CD227,EMA,H23AG,KL-6,MAM6,PEM,PEMT,PUM, Gene summary This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq] Location Chromosome: 1   Locus: 1q21 Gene position 155162700 - 155158300  Map Viewer Gene orientation minus Gene size 4401 bp Gene sequence >MUC1:complement(6646942..6651342):Length=4401 ACCTCTCAAGCAGCCAGCGCCTGCCTGAATCTGTTCTGCCCCCTCCCCACCCATTTCACC ACCACCATGACACCGGGCACCCAGTCTCCTTTCTTCCTGCTGCTGCTCCTCACAGTGCTT ACAGGTGAGGGGCACGAGGTGGGGAGTGGGCTGCCCTGCTTAGGTGGTCTTCGTGGTCTT TCTGTGGGTTTTGCTCCCTGGCAGATGGCACCATGAAGTTAAGGTAAGAATTGCAGACAG AGGCTGCCCTGTCTGTGCCAGAAGGAGGGAGAGGCTAAGGACAGGCTGAGAAGAGTTGCC CCCAACCCTGAGAGTGGGTACCAGGGGCAAGCAAATGTCCTGTAGAGAAGTCTAGGGGGA AGAGAGTAGGGAGAGGGAAGGCTTAAGAGGGGAAGAAATGCAGGGGCCATGAGCCAAGGC CTATGGGCAGAGAGAAGGAGGCTGCTGCAGGGAAGGAGGCGGCCAACCCAGGGGTTACTG AGGCTGCCCACTCCCCAGTCCTCCTGGTATTATTTCTCTGGTGGCCAGAGCTTATATTTT CTTCTTGCTCTTATTTTTCCTTCATAAAGACCCAACCCTATGACTTTAACTTCTTACAGC TACCACAGCCCCTAAACCCGCAACAGTTGTTACGGGTTCTGGTCATGCAAGCTCTACCCC AGGTGGAGAAAAGGAGACTTCGGCTACCCAGAGAAGTTCAGTGCCCAGCTCTACTGAGAA GAATGCTGTGAGTATGACCAGCAGCGTACTCTCCAGCCACAGCCCCGGTTCAGGCTCCTC CACCACTCAGGGACAGGATGTCACTCTGGCCCCGGCCACGGAACCAGCTTCAGGTTCAGC TGCCACCTGGGGACAGGATGTCACCTCGGTCCCAGTCACCAGGCCAGCCCTGGGCTCCAC CACCCCGCCAGCCCACGATGTCACCTCAGCCCCGGACAACAAGCCAGCCCCGGGCTCCAC CGCCCCCCCAGCCCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCAC CGCCCCCCAAGCCCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCAC CCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCACCGCCCCCCCAGC CCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCACCGCCCCCCCAGC CCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCACCGCCCCCCCAGC CCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCACCGCCCCCCCAGC CCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCACCGCCCCCCCAGC CCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCACCGCCCCCCCAGC CCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCACCGCACCCCCAGC CCACGGTGTCACCTCGGCCCCGGACACCAGGCGGGCCCCGGGCTCCACCCCGGCCCCGGG CTCCACCGCCCCCCCAGCCCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCCCGGG CTCCACCGCCCCCCCAGCCCATGGTGTCACCTCGGCCCCGGACAACAGGCCCGCCTTGGG CTCCACCGCCCCTCCAGTCCACAATGTCACCTCGGCCTCAGGCTCTGCATCAGGCTCAGC TTCTACTCTGGTGCACAACGGCACCTCTGCCAGGGCTACCACAACCCCAGCCAGCAAGAG CACTCCATTCTCAATTCCCAGCCACCACTCTGATACTCCTACCACCCTTGCCAGCCATAG CACCAAGACTGATGCCAGTAGCACTCACCATAGCACGGTACCTCCTCTCACCTCCTCCAA TCACAGCACTTCTCCCCAGTTGTCTACTGGGGTCTCTTTCTTTTTCCTGTCTTTTCACAT TTCAAACCTCCAGTTTAATTCCTCTCTGGAAGATCCCAGCACCGACTACTACCAAGAGCT GCAGAGAGACATTTCTGAAATGGTGAGTATCGGCCTTTCCTTCCCCATGCTCCCCTGAAG CAGCCATCAGAACTGTCCACACCCTTTGCATCAAGCCTGAGTCCTTTCCCTCTCACCCCA GTTTTTGCAGATTTATAAACAAGGGGGTTTTCTGGGCCTCTCCAATATTAAGTTCAGGTA CAGTTCTGGGTGTGGACCCAGTGTGGTGGTTGGAGGGTGGGTGGTGGTCATGACCGTAGG GAGGGACTGGTGCACTTAAGGTTGGGGGAAGAGTGCTGAGCCAGAGCTGGGACCCGTGGC TGAAGTGCCCATTTCCCTGTGACCAGGCCAGGATCTGTGGTGGTACAATTGACTCTGGCC TTCCGAGAAGGTACCATCAATGTCCACGACGTGGAGACACAGTTCAATCAGTATAAAACG GAAGCAGCCTCTCGATATAACCTGACGATCTCAGACGTCAGCGGTGAGGCTACTTCCCTG GCTGCAGCCCAGCACCATGCCGGGGCCCCTCTCCTTCCAGTGTCTGGGTCCCCGCTCTTT CCTTAGTGCTGGCAGCGGGAGGGGCGCCTCCTCTGGGAGACTGCCCTGACCACTGCTTTT CCTTTTAGTGAGTGATGTGCCATTTCCTTTCTCTGCCCAGTCTGGGGCTGGGGTGCCAGG CTGGGGCATCGCGCTGCTGGTGCTGGTCTGTGTTCTGGTTGCGCTGGCCATTGTCTATCT CATTGCCTTGGTGAGTGCAGTCCCTGGCCCTGATCAGAGCCCCCCGGTAGAAGGCACTCC ATGGCCTGCCATAACCTCCTATCTCCCCAGGCTGTCTGTCAGTGCCGCCGAAAGAACTAC GGGCAGCTGGACATCTTTCCAGCCCGGGATACCTACCATCCTATGAGCGAGTACCCCACC TACCACACCCATGGGCGCTATGTGCCCCCTAGCAGTACCGATCGTAGCCCCTATGAGAAG GTGAGATTGGGCCCCACAGGCCAGGGGAAGCAGAGGGTTTGGCTGGGCAAGGATTCTGAA GGGGGTACTTGGAAAACCCAAAGAGCTTGGAAGAGGTGAGAAGTGGCGTGAAGTGAGCAG GGGAGGGCCTGGCAAGGATGAGGGGCAGAGGTCAGAGGAGTTTTGGGGGACAGGCCTGGG AGGAGACTATGGAAGAAAGGGGCCCTCAAGAGGGAGTGGCCCCACTGCCAGAATTCCTAA AAGATCATTGGCCGTCCACATTCATGCTGGCTGGCGCTGGCTGAACTGGTGCCACCGTGG CAGTTTTGTTTTGTTTTGCTTTTTTGCACCCAGAGGCAAAATGGGTGGAGCACTATGCCC AGGGGAGCCCTTCCCGAGGAGTCCCAGGGGTGAGCCTCTGTGCCCCTAATCATCTCCTAG GAATGGAGGGTAGACCGAGAAAGGCTGGCATAGGGGGAGGTTTCCCAGGTAGAAGAAGAA GTGTCAGCAGACCAGGTGAGCGTGGGTGCCAGTGGGGTTCTTGGGAGCTTCAAGGAAGCA AGGAACGCTCCCTCCTTCCTCTCCTGGTCTTTCTCTATGGGACCTAGTAAATAATTACTG CAGCCACCTGAGGCTGGAAAACCACTCCAGGTGGGGGAGGAGAGAGTTTAGTTTTCTTGC TCCTATTTTCCTCCTCCTGGAGACCTCCCTCTCTCGGCTTTACAAAGACACAGATACACC CCGCCCCCCAAAACACACACACACACACACACACACCTCCTTAGGCTGGAACAGCAGAGA ATGGAGGGACAAGGGGGCTGATTAGAGCCAAGAAGAGGGAGTGAAGGAGAGCAGAGGGAG GAGGGCAGCCCTGTTTACAGTCACCTGGCTGGTGGGGTGGCAGGTGCTCTCTCTGAATTA ACCCTTTGAGAGCTGGCCAGGACTCTGGACTGATTACCCCAGCCTGGGGTGGCATCCAGG GGCTCTAGGAGGTACCTTTTGCTCCTCACCCTGGATCTCTTTTCCTTCCACCCAGGTTTC TGCAGGTAATGGTGGCAGCAGCCTCTCTTACACAAACCCAGCAGTGGCAGCCACTTCTGC CAACTTGTAGGGGCACGTCGCCCGCTGAGCTGAGTGGCCAGCCAGTGCCATTCCACTCCA CTCAGGTTCTTCAGGGCCAGAGCCCCTGCACCCTGTTTGGGCTGGTGAGCTGGGAGTTCA GGTGGGCTGCTCACAGCCTCCTTCAGAGGCCCCACCAATTTCTCGGACACTTCTCAGTGT GTGGAAGCTCATGTGGGCCCCTGAGGGCTCATGCCTGGGAAGTGTTGTGGTGGGGGCTCC CAGGAGGACTGGCCCAGAGAGCCCTGAGATAGCGGGGATCCTGAACTGGACTGAATAAAA CGTGGTCTCCCACTGCGCCAA OMIM ID 158340