Entrez gene ID | | 4591 |
Official gene symbol | | TRIM37 |
Full name | | tripartite motif-containing 37 |
Aliases | | ,KIAA0898,MUL,POB1,TEF3, |
Gene summary | | This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q23.2 |
Gene position | | 57184266 - 57059999 Map Viewer |
Gene orientation | | minus |
Gene size | | 124268 bp |
Gene sequence |
| |
OMIM ID | | 605073 |
|